Clinical data Clinical trials of St. John's wort use in HIV are limited by the prevalence of interactions between St. John's wort and standard HIV therapy. In 1999, a phase 1 study evaluating hypericin's effects in 30 patients concluded that hypericin had no antiretroviral activity, with ...
Objective: To investigate if extracts of Hypericum perforatum (St John9s wort) are more effective than placebo in the treatment of depression, are as effective as standard antidepressive treatment, and have fewer side effects than standard antidepressant drugs.Design: Systematic ...
St. John's wort (Hypericum perforatum), an herbal therapy that’s been shown in studies to lift symptoms of minor to moderatedepression, has been used in Europe for centuries. Minor to moderatedepressionis a common disorder that's underdiagnosed and undertreated. Not only can minor to moderate...
Side effects; History of the use of the medicinal plant; Clinical trials of St John's wort.LindeKlausRamirezGilbertEBSCO_AspBmj British Medical JournalLinde K, Ramirez G, Mulrow CD, Pauls A, Weidenhammer W, Melchart D. St John's wort for depression--an overview and meta-analysis of ...
Dion Smyth
The effect of St John’s wort extracts on CYP3A: a systematic review of prospective clinical trials. Br J Clin Pharmacol. 2006; 62 :512–526. doi: 10.1111/j.1365-2125.2006.02755.x. [ Cross Ref ]Whitten DL, Myers SP, Hawrelak JA, Wohlmuth H (2006) The effect of St John’s wort ...