Common side effects of St. John's wort may include: sleep problems (insomnia), strange dreams; feeling anxious, irritable, or restless; dry mouth, upset stomach, diarrhea; skin rash, tingly feeling; headache, dizziness; or tired feeling. ...
The following medications are especially dangerous when mixed with St. John’s wort: Antidepressants, Digoxin, Immunosuppressive medications, protease inhibitors (such as Indinavir), Loperamide, Oral contraceptives, Reserpine, Theophylline, Warfarin, epilepsy medications, and medications used in surgery. The...
Although the benefits of St. John's wort are still being explored, research suggests the herb can be more effective than a placebo in alleviating mild to moderate depression. A 2015 review published in theAnnals of Family Medicineexamined whether antidepressants were more effective than a placebo ...
doi:http://dx.doi.org/10.1136/bmj.318.7192.1188Ron LawBMJ
Although not all side effects are known, St. John's wort is thought to be likely safe when taken by an adult for up to 12 weeks, or by a child age 6-17 for up to 8 weeks. St. John's wort may be unsafe when taken in large doses. ...
There is some scientific evidence that St. John's wort may help treat milddepression, with benefits similar to those ofantidepressants. But two large studies, one sponsored by the National Center for Complementary and Alternative Medicine (NCCAM), showed that the herb wasn't more effective than...
The present study provides conclusive evidence that St John's Wort is an effective antidepressant with relatively benign side-effects, and may be a better choice for the treatment of mild – moderate depression than synthetic antidepressants.Wheatley...
Is St John's wort (hypericum) an effective treatment for major depression?EdzardErnstBMJEvidence Based Mental HealthErnst E. Review: St John's wort superior to placebo and similar to antidepressants for major depression but with fewer side effects. Evid Based Ment Health 2009;12(3): 78....
Serious Side Effects Seen With Herbal Supplement Added to Depression TxDa Hee HanPharmD