state and technical noise matrices, which are the two low-dimensional representations of different cells, and an imputed and batch-corrected count matrix in which modalities and features missing from the input data are interpolated and batch effects are removed. These outputs can be used for downstr...
a, 3D UMAP of 1,000 simulated cells with their velocity vectors, using DynGen66. Colors reflect DynGen ground truth branch assignment. CellRank models cell state transitions directly in high-dimensional gene expression space.b, A reference cell i with velocity vectorviand its nearest neighbors. The...
CellRank 2 models cell-state dynamics from multiview single-cell data. It automatically determines initial and terminal states, computes fate probabilities, charts trajectory-specific gene expression trends and identifies lineage-correlated genes (Methods). A broad and extensible range of biological scenari...
Additionally, data is wrapped in a concurrency::array_view exposing it in a multi-dimensional way. For data with Rank=1, however, programmers are accustomed to specifying size & index using integer values (e.g. when using std::vector). This blog will look at some ways in which C++ AM...
Sign in to download full-size image Figure 5.10. Examples of fixed array detectors (A, B) and adaptive array detectors (C, D) for four-slice MSCT scanners. (A) Four 5-mm detectors built out of four linked 1.25-mm elements. (B) Paired linking of the inner eight elements to act as ...
To distinguish between slightly modified polymers, SCNPs and multi-chain clusters, a careful choice of characterization methods is required. In view of future applications, exclusive single-chain systems are not always essential. Even more so, small multi-chain nanoparticles may also offer advantages,...
C family has been received extensive attention because of its low cost, long service life and high oxygen reduction reaction activity in recent years. In order to further enhance the ORR activity, the synthesis method, morphology regulation and catalytic mechanism of the active sites in Fe-N-C ...
array due to the presence of single nucleotide polymorphisms (SNPs) or small insertion/deletions (InDels). Using this approach, thousands of genes can be queried and simultaneously analyzed allowing whole genome approaches to mapping genes and quantitative trait loci (QTL) discovery [6], as well ...
Meier, W., Nardin, C. & Winterhalter, M. Reconstitution of channel proteins in (polymerized) ABA triblock copolymer membranes. Angew. Chem. Int. Ed. 39, 4599–4602 (2000). CAS Google Scholar Hyde, J. R. et al. Formation of array of membranes and apparatus therefor. WO2014064443A3 ...
To model this, we think of protein transport from cell i to cell j as a simultaneous decay of protein in cell i and creation of protein in cell j. Specifically, we can write the system in cell i as: $$\emptyset \begin{array}{*{20}{c}} {v_0} \\ \rightleftharpoons \\ {d_...