A major depressive episode can be categorised as severe based on depressive symptoms, scores on depression rating scales, the need for hospitalisation, depressive subtypes, functional capacity, level of suicidality and the impact that the depression has on the patient. Several biological, psychological ...
Although large genome-wide association studies (GWAS) of major depressive disorder (MDD) have identified many significant loci, the SNP-based heritability remains notably low, which might be due to etiological heterogeneity in existing samples. Here, we test the utility of targeting the severe end ...
Network Open Research July 8, 2024 Mental Health Service Use Before First Diagnosis of a Psychotic Disorder JAMA Psychiatry Research June 18, 2024 Select Your Interests Others Also Liked Multiple Complement Pathway-related Proteins Might Regulate Immunopathogenesis of Major Depressive Disorder Preethi V....
Severe depression : specific features of bipolar disorder Bipolar depressions can present all the clinical aspects from a major depressive episode with a mild intensity to severe one. However, part of this severit... C Henry - 《L Encéphale》 被引量: 3发表: 2009年 加载更多来源...
Heterogeneity in 10-Year Course Trajectories of Moderate to Severe Major Depressive Disorder: A Danish National Register-Based Study (vol 73, pg 346, 2016) Heterogeneity in 10-year course trajectories of moderate to severe major depressive disorder: a danish national register-based study. JAMA Psych...
(A ketamine-derived drug called esketamine is approved for some people as part of treatment-resistant major depressive disorder in a certified clinical setting.) But doctors have developed a protocol for medically supervised use that research shows may help some people who don’t get relief from ...
Coping was assessed among 70 psychiatric inpatients diagnosed primarily with schizophrenia, major depressive disorder, and schizoaffective disorder. The Brief COPE—a questionnaire developed in health psychology (C. S. Carver, 1997)—was administered in interviewer-assisted format during patients' stay ...
published online 2 May 2012 Keywords: PPAR-gamma; pioglitazone; major depressive disorder; adjunctive therapy; thiazolidinedione; randomized controlled trial INTRODUCTION Despite the advent of several antidepressant medications, the treatment of major depressive disorder (MDD) is still far from optimal (Ward...
The secondary and tertiary outcomes were severity of depressive symptoms according to the Major Depression Inventory, adherence to medical treatment, and satisfaction with treatment according to the total score on the Verona Service Satisfaction Scale-Affective Disorder (VSSS-A). These outcomes were ...
has announced receipt of 510(k) clearance from the US Food and Drug Administration (FDA) for itsSAINT neuromodulation systemfor the treatment of major depressive disorder (MDD) in adults who have failed to achieve satisfactory improvement from prior antidepressant medications in ...