冠状病毒SARS-CoV-2核衣壳蛋白(S2NP)是该疾病的主要驱动因子，也是病毒复制和组装不可或缺的结构蛋白，但其在ROS生成中的作用尚未报道。2023年11月，华中科技大学同济医学院基础医学院刘超红教授团队在Journal of Medical Virology (IF 12.7) 上发表文章“SARS-CoV-2 nucleocapsid protein enhances the level of mi...
Coronavirus SARS‐CoV‐2 spike (S) protein and nucleocapsid (N) protein generate immune responses, inducing IgA, IgM, and IgG antibodies, making both targets for vaccines.
SARS-CoV-2 is a betacoronavirus that emerged in China in December 2019 and which is the causative agent of the Covid-19 pandemic. This enveloped virus contains a large positive-sense single-stranded RNA genome. In this review, we summarize the current knowledge on the molecular mechanisms for...
摘要 The Nucleocapsid Protein (NP) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is not only the core structural protein required for viral packaging, but also participates in the regulation of viral replication, and its post-translational modifications such as phosphorylation have ...
SARS-CoV-2 IgG/IgM Rapid Antibody Test Sir, Since December 2019 the novel coronavirus SARS-CoV-2 has emerged as the cause of a pandemic disease known as coronavirus disease 19 (COVID-19).1 On February 21th 2020 the outbreak began in Italy, presently the world's worst affected country.2...
The epidemiology of community‐acquired respiratory viruses during the SARS‐CoV‐2 pandemic In regions of high COVID endemicity, the incidence of other respiratory viral illnesses is depressed, which may reflect biologic displacement of other pathogens or the impact of preventive strategies to reduce...
E3 ubiquitin ligase FBXO22 inhibits SARS‐CoV‐2 replication via promoting proteasome‐dependent degradation of NSP5 E3泛素连接酶FBXO22通过促进NSP5的蛋白酶体依赖性降解抑制新型冠状病毒复制 相关领域 泛素 蛋白酶体 泛素连接酶 病毒复制 生物 调节器 蛋白质降解 细胞生物学 基因敲除 病毒蛋白 病毒学 病毒...
Short‐term exposure to elevated PM and B(a)P levels can be associated with a worse clinical course of COVID‐19 in patients requiring hospitalization and, ultimately, contribute to the health burden caused by SARS‐CoV‐2 variants of higher and lower clinical significance. 展开 关键词: air...
We compared virus detection in air samples between hospitalized patients infected with different SARS‐CoV‐2 variants or influenza virus. The study was performed during three separate time periods in which subsequently the alpha, delta, and omicron SARS‐CoV‐2 variants were predominant. In total, ...
In June 2020, she was detected positive for SARS-CoV-2 specific antibodies (quantitative ratio 5.22 (Wantai SARS-CoV-l2 total Ab ELISA (Beijing Wantai Biological Pharmacy Enterprise), neutralizing antibody titer 1:40). Retrospectively, she declared to having had a transient partial loss of ...