When the quantitative RPR card test is performed on patients with syphilis, a fourfold rise in titer in a repeat specimen may suggest an infection, a reinfection, or a treatment failure; a fourfold decrease in titer following treatment for early syphilis usually indicates that therapy was adequate...
Quantitative Test (Titration) Titer Undiluted Reactive 1:4 1:2 Reactive 1:4 1:4 1:8 1:16 Reactive Nonreactive Nonreactive INTERPRETATION OF RESULTS Flocculation of RPR Antigen which appears as black clumps against the white background of the card indicates a Reactive (R) specimen. Slight but...
Conclusion The introduction of automated RPR assays for syphilis could help expediting syphilis testing, reducing workload and interpretation related errors. However, further testing is needed to establish reproducibility and full titer range validation relative to manual RPR.M Shukla...