Here, using a combination of microscopy, live‐cell imaging analysis and mathematical modelling, we identify a role for Mitochondrial Rho GTPase 1 (MIRO1) as an adaptor for microtubule‐dependent peroxisome motility in mammalian cells. We show that MIRO1 is targeted to ...
Here, using a combination of microscopy, live‐cell imaging analysis and mathematical modelling, we identify a role for Mitochondrial Rho GTPase 1 (MIRO1) as an adaptor for microtubule‐dependent peroxisome motility in mammalian cells. We show that MIRO1 is targeted to peroxisomes and alters their...
mirobiologics | micronit | linktech | lifesci | Life Sciences Advanced Technologies | katchem | katena | JCRB | ImmunoPrecise | idex | ID.vet | Ibidi | IZON | ImmunoGuide | Icosagen | immunesystems | HistoBioTec | hamilton | geneaid | GALAB technologies | full moon biosystems | FOCUS ...
Here, using a combination of microscopy, live‐cell imaging analysis and mathematical modelling, we identify a role for Mitochondrial Rho GTPase 1 (MIRO1) as an adaptor for microtubule‐dependent peroxisome motility in mammalian cells. We show that MIRO1 is targeted to peroxisomes and...
Miro (mitochondrial Rho GTPases) a mitochondrial outer membrane protein, plays a vital role in the microtubule-based mitochondrial axonal transport, mitochondrial dynamics (fusion and fission) and Mito-Ca2+ homeostasis. It forms a major protein complex with Milton (an adaptor protein), kinesin and...
Okumoto, K. et al. New splicing variants of mitochondrial Rho GTPase-1 (Miro1) transport peroxisomes. J. Cell. Biol. 217, 619-633 (2018).Okumoto K, Ono T, Toyama R, Shimomura A, Nagata A, Fujiki Y. New splicing variants of mitochondrial Rho GTPase-1 (Miro1) transport peroxisomes. ...
Mitochondrial Rho GTPase 1-Likedoi:10.1007/978-3-319-67199-4_102312Miro (Mitochondrial Rho)
Although mitochondrial inheritance was not dependent upon Ca 2+ binding by the two EF-hands of Gem1p, a functional N-terminal EF-hand I motif was critical for stable expression of Gem1p in vivo . Our results suggest that basic features of Miro protein function are conserved from yeast to ...
mirobiologics | micronit | linktech | lifesci | Life Sciences Advanced Technologies | katchem | katena | JCRB | ImmunoPrecise | idex | ID.vet | Ibidi | IZON | ImmunoGuide | Icosagen | immunesystems | HistoBioTec | hamilton | geneaid | GALAB technologies | full moon biosystems | FOCUS ...
Some studies also include the members of the RHOBTB and Miro families among those proteins; however, these ‘atypical’ GTPases are highly divergent from the rest of the RHO GTPases in terms of structure, overall amino acid homology, subcellular localization, and biological functions [16]. ...