近年研究报道线粒体Rho GTP酶1(mitochondrial Rho-GTPase 1,Miro1)与驱动蛋白连接,调控线粒体沿微管的运动[8-9]。Miro1是一种定位于线粒体外膜的GTP酶,可通过与接头蛋白(Milton)、驱动蛋白重链(kinesin heavy chain,KHC)等蛋白结合,形成功能性复合体,调控线粒体的运动。Fransson等[10]的研究报道Miro1的突变...
Here, using a combination of microscopy, live‐cell imaging analysis and mathematical modelling, we identify a role for Mitochondrial Rho GTPase 1 (MIRO1) as an adaptor for microtubule‐dependent peroxisome motility in mammalian cells. We show that MIRO1 is targeted to peroxisomes and alters their...
MIRO 1 Antibody MIRO-1 Antibody MIRO1 Antibody MIRO1_HUMAN Antibody mitochondrial Rho (MIRO) GTPase 1 Antibody Mitochondrial Rho 1 Antibody Mitochondrial Rho GTPase 1 Antibody Mitochondrial Rho1 Antibody Rac GTP binding protein like protein Antibody Rac-GTP-binding protein-like protein Antibody Ras ho...
View and buy high purity Miro1 Reducer. Promotes mitochondrial Rho GTPase 1 (Miro1) degradation. Cited in 1 publication.
蛋白别名: MIRO-1; mitochondrial Rho (MIRO) GTPase 1; Mitochondrial Rho GTPase 1; rac-GTP binding protein-like protein; Rac-GTP-binding protein-like protein; Ras homolog gene family member T1; ras homolog gene family, member T1 基因别名: ARHT1; MIRO-1; MIRO1; RHOT1 UniProt ID: (Huma...
dMiro;Gem1;hMiro;Miro-1;Miro-2;Mitochondrial Rho GTPase 1-like;RHOT1 (Ras homolog family member T1);RHOT2;Rhot1;Rhot2; Historical Background The Ras superfamily family of small GTPases consists of GTP binding-dependent molecular switches with diverse cellular functions. Two isoforms of an ...
GTPasest】:Cdc42(Cdc42,TC10,TCL,Chp, Wrch.1):Rac(Rac1—3,RhoG);Rho(RhoA—C): Rnd(Rndl,2,Rnd3/RhoE);RhoD(RhoD,RiO; RhoH/TTF;RhoBTB(RhoBTB1,2)和Miro(MiID— l,21. 收稿日期:2003.12.3l 基金项目:国家自然科学基金资助项目(30170475) 作者简介:蔡军(1972--),男,讲师,博士研究生;易静...
Not surpris ingly, neither RhoBTB1 nor RhoBTB2 were found to in teract with the GTPase-binding domain of WASP, PAK1, or Rhotekin, 3 well-known effectors of many typical Rho GTPases[48]. Confirming that, at least in metazoa, RhoBTB proteins do not play a major role in the...
Human Rho GTPases (of which there are 22 members) comprise a main branch of the Ras superfamily of small GTPases and GDP/GTP-regulated molecular switches. Rho GTPases are activated by the direct engagement of guanine nucleotide-exchange factors (GEFs), which catalyse the ejection of GTPase-...
SCAM-124823 Chroman 1 N/A SCAM-124824 Narciclasine 29477-83-6 SCAM-124825 Miro1 Reducer 2624336-91-8 SCAM-124826 Deltarasin 1440898-82-7 SCAM-124827 GW 5074 220904-83-6 SCAM-124828 SB 590885 405554-55-4 SCAM-124829 GDC 0879 905281-76-7 SCAM-124830 AZ 628 878739-06-1 SCAM...