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For simple data reconstruction, this architecture is adequate; however, it is not sufficient for new data generation. The main reason is that the obtained latent space is not uniformly distributed but contains discrete data patches (Kingma and Welling 2014). The interpolation between these patches ...
It harbors a unique open reading frame comprising 675 nucleotides and an internal ribosome entry site, specifically the − 150-bp sequence upstream of the ATG start codon. These attributes confer on circ-EIF6 the capacity to encode the protein EIF6-224aa. Notably, EIF6-224aa impedes the...
Circ Cardiovasc Qual Outcomes. 2019;12:e005616. PubMed Google Scholar Zhou H, Wang X, Yang Y, Chen Z, Zhang L, Zheng C, et al. Effect of a multicomponent intervention delivered on a web-based platform on hypertension control: A cluster randomized clinical trial. JAMA Netw Open. 2022;...
R2C Leydig tumor cells, which constitutively secrete large amounts of steroids, also show extremely high basal levels of SR-B1 protein and mRNA levels, and cAMP treatment modestly increases their levels further (86). It is becoming clear that the physical form of SR-B1 also plays a key ...
Program Associate, Research Synthesis and New Technology, PCORI; and RTI International staff Eva Chang, PhD, Research Associate; Valerie Ng, BS, Research Assistant; Sharon Barrell, MA, Editor; Teyonna Downing, Publications Specialist; and Candi Wines, MPH, and Carol Woodell, BSPH, Program Managers...
Gallagher RI, Wulfkuhle J, Wolf DM, Brown-Swigart L, Yau C, O'Grady N, Basu A, Lu R, Campbell MJ, Magbanua MJ, et al: Protein signaling and drug target activation signatures to guide therapy prioritization: Therapeutic resistance and sensitivity in the I-SPY 2 trial. Cell Rep Med. ...
Young BE, Ong SWX, Kalimuddin S, Low JG, Tan SY, Loh J, Ng O-T, Marimuthu K, Ang LW, Mak TM, Lau SK, Anderson DE, Chan KS, Tan TY, Ng TY, Cui L, Said Z, Kurupatham L, Chen MI-C, Chan M, Vasoo S, Wang L-F, Tan BH, Lin RTP, Lee VJM, Leo Y-S, Lye DC. ...
Current guidelines for pain treatment recommend a personalized, multimodal and interdisciplinary approach as well as the use of a combination of drug and n