Alzheimer's disease articles from across Nature Portfolio Atom RSS Feed Alzheimer's disease is a progressive neurodegenerative disease that impairs memory and cognitive judgment and is often accompanied by mood swings, disorientation and eventually delirium. It is the most common cause of dementia. ...
Better cellular models of Alzheimer's disease? For many years the lack of truly faithful cellular and animal models of AD has imposed some limitation on what can be inferred from these experimental models. With the technological advances demonstrating that human fibroblasts can be converted into plur...
There are various genetic, environmental and dietary risk factors for Alzheimer disease like diabetes, oxidative stress, hypertension, air pollution, hypercholesterolemia, atrial fibrillation, alcohol, smoking,etc. These risk factors have played a very significant role in the development of Alzheimer’s p...
The field of Alzheimer's disease therapeutic research seems poised to bring to clinic the next generation of treatments, moving beyond symptomatic benefits to modification of the underlying neurobiology of the disease. But a series of recent trials has had disappointingly negative results that raise qu...
As co-editors of Alzheimer's Research and Therapy we would like to highlight several of the major translational research advances that have occurred over the past year, during which a tremendous amount of superb science relevant to the study of Alzheimer's disease (AD) has been published. ...
Alzheimer’s disease is caused by the accumulation of two proteins, amyloid beta and tau, within the brain. While the decline in cognitive function is the most well-known symptom of Alzheimer’s disease, this protein accumulation can occur in various locations of the brain, brainstem, and spina...
Alzheimer's disease (AD) is a diverse disease with a complex pathophysiology. The presence of extracellular β-amyloid deposition as neuritic plaques and intracellular accumulation of hyper-phosphorylated tau as neurofibrillary tangles remain the core ne
Third, the clinical symptoms of Alzheimer''s disease (AD) including the physical disabilities that accompany the disease are addressed. Fourth, future directions in disability research in regards to AD are proposed. Disability models that are specific to persons with progressive cognitive disorders ...
. What's different about a special care unit for dementia patients? A comparative study. American Journal of Alzheimer's Disease and Other Dementias, 3(... Laura,Mathew,Philip,... - 《American Journal of Alzheimers Care & Related Disorders & Research》 被引量: 9发表: 2016年 The content ...
关键词: Humans Alzheimer Disease Cholinesterase Inhibitors Apolipoproteins E Behavior Therapy Apolipoprotein E4 Amyloid beta-Peptides National Institutes of Health (U.S Research United States DOI: 10.1111/j.1532-5415.1994.tb06870.x 被引量: 21 ...