by altering the acetylation status of histone cores in the promoter region21. It has also been suggested that HDACs have a role in maintenance of CSCs28. Thus, given their ability to affect the transcription of vital genes and alter the viability of CSCs, HDAC inhibitors are promising candidat...
4.3.1. Alpha’s Healthcare Platform Business Model as the Driver for Exploring New Business Models Alpha had two core integration mechanisms. The first was the genomic project, in which the innovation department provided an inflow of high-value-added services for predictive and precision medicine ...