Glucose in the blood is the energy source for all of the cells in the body. The membranes surrounding the cells prevent glucose from entering, except at specific gate locations. Only when gates are open can glucose be absorbed by the cells. Co-located at the gates are insulin receptors. ...
Regulation of Blood Glucose Levels 来自 Citeseer 喜欢 0 阅读量: 35 作者: NHJRA Harris 摘要: In the well-fed state a relatively high activity of the pyruvate dehydrogenase complex (PDC) reduces blood glucose levels by directing the carbon of pyruvate into the citric acid cycle. In the fasted...
Glucose-responsive insulin delivery systems that mimic pancreatic endocrine function could enhance health and improve quality of life for people with type 1 and type 2 diabetes with reduced β-cell function. However, insulin delivery systems with rapid i
First, the blood–blood barrier, which partitions the circulating blood from the CNS, acts as a gatekeeper to facilitate the selective trafficking of substances between the blood and the parenchyma. Second, neurovascular coupling ensures that, following local neural activation, regional blood flow is ...
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Sampling in the fed state was performed at ZT0 to avoid an apparent effect of fasting. For the glutamine tolerance test, 16-hr fasted mice were administered intraperitoneally with 250 mg/kg glutamine; blood glucose (BG) levels were monitored at the indicated time points. BPTES was pre-...
Lupus nephritis (LN) is a severe and common manifestation of systemic lupus erythematosus (SLE) that is frequently identified with a poor prognosis. Macrophages play an important role in its pathogenesis. Different macrophage subtypes have different effe
View PDFView articleCrossrefView in ScopusGoogle Scholar [2] X. Zhu, X. Sun, M. Wang, C. Zhang, Y. Cao, G. Mo, et al. Quantitative assessment of the effects of beta-glucan consumption on serum lipid profile and glucose level in hypercholesterolemic subjects Nutr Metab Cardiovasc Dis,...
Glucose homeostasis is tightly regulated to meet the energy requirements of the vital organs and maintain an individual’s health. The liver has a major role in the control of glucose homeostasis by controlling various pathways of glucose metabolism, inc
et al. Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock. Cell Rep. 40, 111208 (2022). Article CAS PubMed Google Scholar Tang, H. et al. The solute carrier SPNS2 recruits PI(4,5)P(2) to synergistically regulate transport of ...