Alzheimer's disease also known as dementia is one of the widely affective neurodegenerative disorder only after Parkinsonism. The patients suffering from Alzheimer's disease has increased dramatically over a period of time. This has propelled the interest of neuroscientists to develop new drug therapies...
As co-editors of Alzheimer's Research and Therapy we would like to highlight several of the major translational research advances that have occurred over the past year, during which a tremendous amount of superb science relevant to the study of Alzheimer's disease (AD) has been published. ...
Despite the severe impairment of recent episodic memories in Alzheimer’s disease, there have been few attempts to rehabilitate these deficits. In a follow-up study to previously published papers, we used a novel external memory aid to prom...
Despite the severe impairment of recent episodic memories in Alzheimer’s disease, there have been few attempts to rehabilitate these deficits. In a follow-up study to previously published papers, we used a novel external memory aid t...
Alnylam intends to report preliminary topline results from the Phase 1 study of ALN-APP in patients with early onset Alzheimer’s Disease. Alnylam intends to initiate a Phase 1 study of ALN-KHK in normal healthy volunteers. Vir intends to report ad...
the BPMOs loaded with neutron capture agents provide a method of treating cancer, immunological disorders and other disease by utilizing a neutron capture therapy modality, including but not limited to rheumatoid arthritis, ankylosing spondylitis, and other cellular diseases, and Alzheimer’s disease. ...
Rats (Rattus norvegicus) and mice (Mus musculus) belong to the same rodent family and have been the most widely used models in biomedical research for many years. However, there are several differences between these two animals. For example, the rat is larger (roughly about eight- to ten-fo...
In addition to this, many studies have been reported on related detection devices due to the importance of EEG signals in the diagnosis of Alzheimer’s disease, Parkinson’s disease, epilepsy, etc. [73,74]. Figure 6. (a) Topographic distribution of absolute sleep EEG power (µV2) across...
Xanomeline-Trospium (KarXT) (M1/M4-agonist): In July 2024, Zai Lab joined the global Phase 3 ADEPT-2 study in Alzheimer’s disease with psychosis in Greater China. ZL-1102 (IL-17 Humabody®): In May 2024, Zai Lab dosed the first patient in a global Phase 2 st...
The continuously increasing interest in Amaryllidaceae alkaloids in the last years is based on important pharmaceutical properties. Galanthamine possesses anti-acetylcholinesterase activity, used for the treatment of Alzheimer’s disease, and is approved for use in the European Union and the United States...