Better cellular models of Alzheimer's disease? For many years the lack of truly faithful cellular and animal models of AD has imposed some limitation on what can be inferred from these experimental models. With the technological advances demonstrating that human fibroblasts can be converted into plur...
Recent work on Alzheimer's disease transgenics. Curr. Opin. Biotechnol. 9 (6), 561 - 564.Duff, K. 1998. Recent work on Alzheimer's disease transgenics. Curr. Opin. Biotechnol. 9:561–564.Duff K: Recent work on Alzheimer's disease transgenics. Curr Opin Biotechnol 1998, 9:561-564...
In recent years, Alzheimer's disease has become well known both to the medical profession and to laymen as an increasingly important cause of morbidity and mortality in the elderly. As interest in the disease has grown, so has the scientific literature. In the past four years, over 400 journ...
Amyloidopathies cause neurodegeneration in a substantial portion of the elderly population. Improvements in long term health care have made elderly individuals a large and growing demographic group, marking these diseases as a major public health concern. Alzheimer's Disease (AD) is the most studied...
M Vaz,S Silvestre 摘要: Alzheimer Disease (AD) is a neurodegenerative disease characterized by two neuropathological hallmarks: extracellular deposition of amyloid plaques and intracellular neurofibrillary tangles. Current treatment for AD (donepezil, galantamine, rivastigmine and memantine) is only ...
0 Citations 0 Altmetric Article metrics 科大讯飞翻译(iFLYTEK Translation) Abstract Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases, with a high prevalence among the elderly. However, the mechanism of its occurrence is not clear, and there is a lack of convenient ...
Abraham CR , Potter H ( 1989 ): Alzheimer's disease: Recent advances in understanding the brain amyloid deposits . Biotechnology 7 : 147 – 153 .Biotechnology, volume 7, February 1989, C.R. Abraham et al.: "Alzheimer's disease: Recent advances in understanding the brain amyloid deposits",...
Alzheimer's disease (AD) is an age-related neurodegenerative disorder characterized by progressive memory deficits and other cognitive disturbances. Neuropathologically, AD is characterized by the progressive loss of basal forebrain cholinergic neurons that innervate the hippocampus and cortex and the abno...
Stem cell therapy has been noted to be a disease-modifying treatment for Alzheimer's disease (AD). After the failure to develop new drugs for AD, the number of studies on stem cells, such as mesenchymal stem cells (MSCs) and neural stem cells (NSCs), has increased from the early 2000s...
摘要: Examines the basis of dementia in understanding alzheimer disease. Advancement on the information of the disease; Description on the reduction of activity of the enzyme choline acetyltransferase in cerebral cortex; Suggestion of the result of the neuroanatomical study. 展开 ...