Compound-B," by W.E. Klunk and colleagues, "Tau suppression in a neurodegenerative mouse model improves memory function," by K. SantaCrus and colleagues and "Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Aβ and synaptic dysfunction," by S. Oddo...
Better cellular models of Alzheimer's disease? For many years the lack of truly faithful cellular and animal models of AD has imposed some limitation on what can be inferred from these experimental models. With the technological advances demonstrating that human fibroblasts can be converted into plur...
Alzheimer's disease (AD) is one such condition frequently observed with the aged population and sometimes in youth too. Most of the research utilizes different animal models for in vivo study of AD pathophysiology and to investigate the potency of the newly developed therapy. These in vivo ...
IntroductionGlobalData's report, "Early Diagnosis of Alzheimer's Disease - Benefits, Challenges and Recent Developments" provides key update on the landmark on the early diagnosis of Alzheimer's ...IntroductionGlobalData’s report
including Parkinson’s disease, Huntington’s chorea (Danduga et al.2018), and Alzheimer’s disease. It can also raise plasma concentrations, growth hormone levels, and protein synthesis in the brain (Cho et al.2007). Furthermore, GABA promotes cancer cell death and inhibits cancer cell growth...
Abraham CR , Potter H ( 1989 ): Alzheimer's disease: Recent advances in understanding the brain amyloid deposits . Biotechnology 7 : 147 – 153 .Abraham CR, Potter H (1989) Alzheimer’s disease: recent advances in understanding the brain amyloid deposits. Biotechnology 7:147–153...
Alzheimer's disease (AD) stands as the predominant form of dementia, presenting significant and escalating global challenges. Its etiology is intricate and diverse, stemming from a combination of factors such as aging, genetics, and environment. Our current understanding of AD pathologies involves vari...
Alzheimer's disease (AD) is the most common type of dementia in aging adults, and a substantial burden to patients, caregivers, and the healthcare system. It is an increasingly significant public health issue; with the number of people living with AD projected to increase dramatically over the...
Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases, with a high prevalence among the elderly. However, the mechanism of its occurrence is not clear, and there is a lack of convenient means of early diagnosis, which makes it difficult to intervene in and treat the...
Alzheimer's disease (AD) is an age-related neurodegenerative disorder characterized by progressive memory deficits and other cognitive disturbances. Neuropathologically, AD is characterized by the progressive loss of basal forebrain cholinergic neurons that innervate the hippocampus and cortex and the abno...