Rat liver-targeted naked plasmid DNA transfer by tail vein injection[J] . Hiroki Maruyama,Noboru Higuchi,Shigemi Kameda,Jun-ichi Miyazaki,Fumitake Gejyo.Molecular Biotechnology . 2004 (2)Maruyama H,Higuchi N,Kameda S,etc.Rat liver-targeted naked plasmid DNA transfer by tail vein injection.[J]...
Because of the difficulty in administering SRBC by tail vein injection, the pups received SRBC intraperitoneally but were still unable to generate a primary IgM response. Histologically germinal centers were observed in rat pups immunized with SRBC. Taken together,these results suggest that the spleen...
Background High levels of foreign gene expression in mouse hepatocytes can be achieved by rapid tail vein injection of a large volume of a naked DNA solution, the 'hydrodynamics-based procedure'. Rats are more tolerant of the frequent phlebotomies required for monitoring blood parameters than mice...
This vessel has since proved far more satisfactory than the commonly used tail vein for either bleeding or injection1,2. The technique of injection by this route has been briefly, but obscurely, described2, and it thus remains not generally known. This is a preview of subscription content, ...
To achieve this we used the capacity of AAV9 to cross the BBB in order to deliver GDNF to young SOD1G93A (herein, SOD1) ALS rats using tail vein injection, which in other studies has led to widespread expression of the vector.12,14,17 GDNF administration in this manner resulted in ...
In this study, a cancer model was established by tail vein injection of 2 million NuTu-19 tumor cells. Urine samples were randomly selected from tumor-forming and non-tumor-forming rats on day 0/12/27/39/52 and were analyzed by label-free and parallel reaction monitoring targeted proteomic...
In contrast to CD34− and unsorted ACL-derived stem cells, the CD34+ ACL-derived subpopulation had a higher proliferation rate in vitro and a better in vivo outcome (injection into the joint capsules of reconstructed ACLs). This has been demonstrated by the better functional healing between ...
15. MethodsRatALI model was reproduced by injection of lipopolysaccharide intotailvein. 方法尾静脉注射内毒素制备ali大鼠模型。 youdao 16. Method Type I collagen was attained fromrattailtendon with method of acid extraction, then undergone analysis and identification using ultraviolet spectroscopy, SDS-PAG...
The FITC-inulin solution was sterile filtered (0.2 µm syringe filter) before tail vein injections in conscious rats (100 mg/kg). Sublingual blood was collected in heparinized tubes at 8 timepoints over the course of 75 min post-injection. Plasma FITC-inulin concentrations were measured using...
Nanoparticle targeting to diseased aortas, (n = 6 per group). (a) Nanoparticle accumulation in aorta following systemic intravenous injection of EL-DiR-NP twenty-eight days after adenine feeding. DIR NPs targeted the diseased regions twenty-four hours after delivery in 4 of 6 adenine-fed ...