Enteric-selective inhibition of the JAK/STAT pathway may provide a treatment for FAP. Lorpucitinib is an oral, small molecule, potent pan-JAK inhibitor with favorable enteric-selective properties. Here, we report the efficacy, safety, and pharmacokinetic (PK) results from a phase 1b study of...
Tip 2: Make Green simple! The easier you make your green efforts the easier they are to follow through. For example, place recycling bins next to trash bins in the break room. When your team has a green option right next to the traditional choice, they can make better decisions without ...
and full-year 2023 net result of €7,287 million Quarterly profit before tax increases 31% year-on-year to €2,247 million; CET1 ratio remains strong at 14.7%
被引量: 2发表: 2014年 Unemployment and drilling activity in major energy-producing states This article presents results of an investigation into the sensitivity of unemployment rates in Louisiana, Oklahoma, and Texas to the cycle of oil and gas-... DP Manuel - J. Energy Dev.; (United States...
2023年8月23日,德曲妥珠单抗(T-DXd,DS-8201)在日本获批用于治疗化疗后出现疾病进展的HER2(ERBB2)突变的不可切除晚期或复发性非小细胞肺癌(NSCLC)成人患者。 2023年10月23日,德曲妥珠单抗(T-DXd,DS-8201)在欧盟(EU)获批作为单一疗法,用于治疗存在HER2 ( ERBB2 ) 激活突变,并且在铂类化疗后需要全身治疗(联合...
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IEEE International Conference On Knowledge Graph (ICKG-2023) December 1-2, 2023 Shanghai, China Knowledge Graph deals with fragmented knowledge from heterogeneous, autonomous information sources for complex and evolving relationships, in addition to domain expertise. TheIEEE International Conference on Kno...
The results showed that tea polyphenols content of samples with bifenthrin spraying was significantly lower than that of samples before spraying (P < 0.01). The content of tea polyphenols in the samples with bifenthrin spraying and with beneficial bacterial ...
The results of the study could contribute to knowledge regarding a successful entry into the teaching profession and factors that could help increase the likelihood of job satisfaction and well-being among teachers at the beginning of their career. To ensure a success...
RESULTS. After removal of duplicates, 896 records were screened, 43 studies included a HRQoL endpoint. 8 studies were included in the meta-analysis after exclusion for insufficient data (n=10) or power (n=25). 3 of these did not meet the MCID (>33m) for six-minute walk distance (6...