Even when distant metastases to the liver or lungs are known to be present, there is merit in removing the primary tumor to prevent later obstruction of the colon and hemorrhage, and to reduce the tumor burden prior to chemotherapy. The presence of a large rectal cancer usually requires ...
-localized is most common site distal mets —> primary resection provided that primary cancer curatively resected and no major venous/portal vein/hepatic artery involvement 5 yr survival 40%Same goes for lungs Therapy for un-resectable metastatic disease Palliative chemo:-5fU maninstay +comined ...