PJX PJY PK PK/A PK/H PK/NF PK/PD PK/PE PK/PF PK/PK PK1 PK3 PK5 PKA PKAc PKAcs PKAD PKAF PKAI PKAIET PKAL PKAN PKAO PKAP PKARC PKAS PKASSO PKAT PKAVS PKAW PKB PKBD PKBF PKBG PKBI PKBL PKBM PKBN PKBR ▼
The invention provides a compound of the formula (I) or a salt, solvate, tautomer or N-oxide thereof; wherein A is a saturated hydrocarbon linker group; E is a monocyclic or bicyclic carbocyclic or heterocyclic group; L1 is a bond or a linker selected from C1-C4 alkenylene, C1-C4 ...
H-89, Dihydrochloride又称为H 89 2HCl,是一种有效的、细胞通透性蛋白激酶A(PKA)抑制剂,Ki值为48 nM,通过与ATP竞争性结合PKA催化亚基,抑制PKA磷酸化作用。H-89, Dihydrochloride还可抑制S6K1、MSK1、ROCK-II、PKBα和MAPKAP-K1b等激酶活性,IC50依次为80、120、270、2600和2800 nM。另外,H-89, Dihydrochloride...
AT13148 是一种 ATP 竞争性 AGC 激酶口服抑制剂,能够抑制 Akt1/Akt2/Akt3、p70S6K、PKA 和 ROCKI/ROCKII 的活性,IC50值分别为 38/402/50、8、3 和 6 nM/4 nM。 规格价格库存数量 1 mg ¥ 392 现货 2 mg ¥ 576 现货 5 mg ¥ 892 现货 10 mg ¥ 1,380 现货 25 mg ¥ 2,480...
AT7867 是 ATP 竞争性的Akt1/Akt2/Akt3和p70S6K/PKA 抑制剂,IC50分别为 32、17、47 和 85、20 nM。
pOH=pKb+log([ConjugateAcid][Base]) Next, we will go over two example problems that show how to apply the Henderson-Hasselbalch equation. Example Problem 1 - Acid/Conjugate Base Solution Hydrofluoric acid has a pKa of 3.10. When the acid is dissolved in a solution with a...
The acid in vinegar has a pKa value of 1.85 x 10^-5 at 25 degrees C. Find the pKb value of its conjugate base. What are the steps and formulas to calculate pK_a or pK_b values for weak acids or bases. What hydrogen atoms in the given compound have a pKa less ...
Fig.1ThestructuralformulaofsubstitutedPyridine 1 计算方法 1.1 量化参数计算法 使用Gaussion09W软件,构建24个已知实验 pK.值的取代吡啶的分子结构模型,然后在 DFT/B3LYP/3—21G理论水平下,优化它们的结构, 计算得到相对应的量化参数,分别记录吡啶及其取
Find the pKb value of its conjugate base. A weak acid has a pKa of 6.0. What is the ratio of conjugate acid to conjugate base at pH = 5? During your titration, you overshot your endpoint and your solution was too pink. Would this ...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook protein kinase (redirected fromPKA) Medical Acronyms Encyclopedia Wikipedia protein kinase n. Any of a group of kinases that phosphorylate the amino acids serine, threonine, and tyrosine in certain proteins, that ...