developed another annulation reaction, based on the metalation of phenyl acetates 105, using the Rh(II)/HCO2H catalytic system. The ortho-CH bond activation of 105 by [Rh2(OAc)4] allowed the insertion of cinnamate 106 into the aromatic ring, which in the final step produces additional ...
Gadakh et al. developed another annulation reaction, based on themetalationofphenyl acetates105, using the Rh(II)/HCO2H catalytic system. Theortho-CH bond activation of105by [Rh2(OAc)4] allowed the insertion ofcinnamate106into thearomatic ring, which in the final step produces additional form...
Using Acromobacter eurydice isolated from soil, we clarified the pathway by which phenylpyruvate is metabolized to phenylacetate through phenylacetaldehyde. We defined the enzymes concerned as phenylpyruvate decarboxylase and phenylacetaldehyde dehydrogenase. Phenylpyruvate decarboxylase was purified and some of...
Paraoxonase activity was measured spectrophotometrically in 50 mM glycine/NaOH buffer (pH 10.5) containing 1.0 mM paraoxon, and 1.0 mM CaCl2. Arylesterase activity was measured in 20 mM TrisCl buffer (pH 8.0) containing 1 mM phenyl acetate and 1 mM CaCl2. PON1 activity toward paraoxon and ...
Paraoxonase activity was measured spectrophotometrically in 50 mM glycine/NaOH buffer (pH 10.5) containing 1.0 mM paraoxon, and 1.0 mM CaCl2. Arylesterase activity was measured in 20 mM TrisCl buffer (pH 8.0) containing 1 mM phenyl acetate and 1 mM CaCl2. Results PON1 activity toward paraoxon...
After stirring at room temperature overnight, % NaOH solution was added until pH 8-10. The mixture was extracted with CH2Cl2. The organic phase was dried with Na2SO4 and the solvent was removed under reduced pressure. The crude products were crystallized from methanol-ethyl acetate 1:1 ...
It has been reported that tetraalkylammonium fluorides, cyanides or acetates frequently offer considerable advantages over the hydroxides in terms of derivatization selectivity without compromising derivatization efficiency. Regarding on-column benzylation reagents, the 3,5-bis(trifluoromethyl)benzyl...
(E)-2-methoxyimino-N-methyl-2-(2-phenoxyphenyl)-acetamide; 8-hydroxyquinoline sulphate; methyl (E)-2-{2-[6-(2-cyanophenoxy)-pyrimidin-4-yloxy]-phenyl}-3-methoxyacrylate; methyl (E)-methoximino-[alpha-(o-tolyloxy)-o-tolyl]-acetate; 2-phenylphenol (OPP), aldimorph, ampropylfos, ...
Procedure A. In a first procedure for the preparation of N-trityl-N-carboxyanhydrides, by the appropriate N-trityl-amino acid (14 mmol) was added to a solution of triphosgene (1.51 g, 5.6 mmol) in ethyl acetate (280 mL). The resulting solution was treated by the dropwise addition of 1...
The solvent was removed under reduced pressure and ethyl acetate added to give a suspension which was vigorously stirred for 15 minutes. Once the suspension had settled the ethyl acetate was decanted off and washed with water and saturated brine, dried over sodium sulphate, filtered and the ...