PDC 的氧化能力和反应溶剂有关,PDC用DMF当溶剂可以将伯醇氧化为酸,而在 CH2Cl2 中则将伯醇、仲醇、苄醇和烯丙基醇稳定地转变为相应的醛酮化合物。通过选用不同的溶剂,PDC 许多时候可以取代 PCC 和 MnO2 在有机合成中的许多功能。另外PDC还可将环状半缩醛氧化成为相应的内酯或者内酰胺,在叔丁基过氧化氢帮助下...
Pyridinium chlochromate (PCC), in refluxing benzene, or dimethyl sulfoxide, and pyridinium dichromate (PDC) in pyridine, have been found to be effective reagents for the allylic oxidation of Δ5-steroids to yield the corresponding α, β - unsaturated ketones.Edward...
In DMF, the reaction of primary alcohols with PDC (except for ally alcohols) leads to complete oxidation to carboxylic acids. These chromium-based reagents are used less frequently today with the development of milder and less toxic oxidation reagents. ...