The HPD software provides both a user-friendly Web interface for online use and a robust relational database backend for advanced pathway querying. This pathway tool enables users to 1) search for human pathways from different resources by simply entering genes/proteins involved in pathways or ...
Reactive oxygen species (ROS) are generated by virus-infected cells; however, the physiological importance of ROS generated under these conditions is unclear. Here we found that the inflammation and cell death induced by exposure of mice or cells to sources of ROS were not altered in the absence...
amino acid groups displayed enhanced activity in varying degrees when tested against two cancer cell lines, with IC50 values ranging from 11.41 ± 0.77 to 42.44 ± 1.16 µM. Table 1. Anti-proliferative activities of compounds 3a–3z. Compounds IC50 (µM) a HepG2 MCF-7 Compounds IC50 (...
The liver, kidney, lung, and paracancerous colon tissues of nude mice were analyzed by HE staining (Figure 10). Observation of the nude mice’s colon sections revealed the nude mice’s colon tissue glands were intact, but they were arranged loosely with various degrees of gland atrophy. The...
Figure 7. (A) HRA + OCT imaging with a Spectralis HRA+ device Binarized optical coherence tomography pictures with varying degrees of DR severity, as well as non-segmented angiograms, are shown in (B). (a) There is no DR. (b) Mild NPDR if any. (c) NPDR of a moderate level. (d...
Fisher's combined probability test, where the test statistic, Tcomb is calculated as: Tcomb = −2 × ln(Pm) + ln(Pg) (1) Tcomb follows a χ2 distribution with 2 degrees of freedom and the associated p-value, Pcomb, is calculated using the R function pchisq() and 2 degrees of ...