Paracetamol overdoseThe article describes the case of a 36-year-old man who developed acute liver failure and brain oedema after ingesting an overdose of paracetamol.Reactions Weekly
UrineIn rats, the biliary and renal excretion of paracetamol changed in a dose-dependent manner. After an oral nonhepatotoxic dose of 200 mg/kg paracetamol, the drug excreted in the bile amounted to only 5.5% within 24 h, whereas 72% of the dose were excreted into the urine. Following ...