多耐药基因 6) Multi-drug resistance gene 多药耐药基因 1. Relationship between multi-drug resistance gene polymorphism and blood concentration of ciclosporin in renal transplantation patients; 肾移植中环孢素的血药浓度与多药耐药基因多态性的关系
摘要:目的观察siRNA沉默COX-2基因增强口腔癌耐长春新碱细胞株KB/VCR对长春新碱的敏感性。方法将KB/VCR细 胞分为COX-2siRNA组、阴性对照组及空白对照组,RT-PCR检测COX-2mRNA和MDR-1mRNA的表达,流式细胞术检测细 胞内Rho-123的蓄积量,MTT法检测细胞活力。结果COX-2siRNA能增强长春新碱对KB/VCR细胞的生长抑制...
多药耐药基因 1. Relationship between multi-drug resistance gene polymorphism and blood concentration of ciclosporin in renal transplantation patients; 肾移植中环孢素的血药浓度与多药耐药基因多态性的关系 2. Relationship between multi-drug resistance gene MDR1 and NF-kappa B in human drug-resistance ...