G Colak,GVW Johnson - 《Neurobiology of Disease》 被引量: 52发表: 2012年 The Advanced Technology Solar Telescope: beginning construction of the world's largest solar telescope The 4m Advance Technology Solar Telescope (ATST) will be the most powerful solar telescope and the world's leading grou...
Alzheimer’s disease APP: Amyloid precursor protein BACE1: Beta-secretase 1 BDNF: Brain-derived neurotrophic factor CA3: Cornu amonis CAT: Catalase CCL4: Carbon tetrachloride CNS: Central nervous system COMT: Catechol-O-methyltransferase EMM: Ectomycorrhizal mushrooms GDNF: Glia-derived ...
It is a parasympathomimetic acetylcholine precursor and various studies have reported its potential for the treatment of Alzheimer's disease and other dementias. It has been reported to improve the cognitive functions as well as learning and memory capacities (Drago et al., 1992; Sigala et al....
In plants, a putative dual-specificity protein phosphatase (IBR5, 257aa), part of a SCF protein ligase complex that when mutated alters response to indole-3-butyric acid (IBA). Dephosphorylates and inactivates MAP kinase MPK12. IBD (1) Inflammatory bowel disease. See Crohn’s disease and ...
BACH1 (BTB and CNC homology 1 transcription factor) and ERG (Ets family of transcription factors) may play a role in the development of Alzheimer's disease associated to DS (Ferrando-Miguel et al., 2003; Shim et al., 2003). Noncoding RNAs (ncRNAs) are transcripts that do not code ...
Sirtuin 1 and Alzheimer's disease: An up-to-date review Liara Rizzi, Matheus Roriz-Cruz, in Neuropeptides, 2018 1 Research in context Sirtuins are nicotinamide adenine dinucleotide (NAD+) dependent enzymes (Herskovits and Guarente, 2013). In terms of their evolution, they are highly conserved...
Lipids and Alzheimer's Disease Akhlaq A. Farooqui, ... Tahira Farooqui, in Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2010 In neural cell cultures at plasma membrane level, low levels of ceramide mediate differentiation and neuritic outgrowth through it action...
Finally, one study used diffusion tensor imaging (DTI) features coupled with WM integrity analysis to distinguish between late-onset bipolar disorder, Alzheimer’s Disease (AD) and HC. Using an SVM algorithm trained and tested on fractional anisotropy (FA), the authors achieved 100% accuracy in ...
Prion diseases are infectious diseases in which the transmissible protein agent may catalyze misfolding of endogenous proteins. In Alzheimer's disease, deposits of amyloid may contribute to pathogenesis. Polyglutamine diseases result from genetic expansion of repeat units encoding glutamine and are ...
On the basis of these findings, a large international, randomized, double-blind phase III trial (START trial) evaluated tecemotide as maintenance therapy in patients with unresectable stage III NSCLC who had completed chemoradiotherapy with confirmed stable disease or an objective response.84 The study...