We studied proliferation and apoptosis in oligodendrogliomas and their relationship to progression of the tumours. Thirty-two cases of oligodendroglioma were retrieved spanning a 10-year period. The diagnosis and grade were reviewed and follow-up data obtained. Mitotic index (MI) and apoptotic index ...
many of the tumors progress, eventually leading to patient death. To characterize the changes associated with oligodendroglioma recurrence and progression, we analyzed two recurrent oligodendroglioma tumors upon diagnosis and after tumor relapse based on whole-genome and RNA sequencing. Relapsed...
diagnosed anaplastic oligodendroglioma harboring a chromosome 1p deletion is so likely to be chemosensitive and have prolonged survival that the best therapy may consist of early postoperative chemotherapy using PCV together with radiotherapy or using PCV alone until there is evidence of tumor progression...
Progression-free survival (PFS) and overall survival (OS) were evaluated using Kaplan–Meier analysis. Univariate and multivariate Cox regression analyses were utilized to identify significant prognostic factors. Results In the gross total resection (GTR) group, 63 (45.7%) underwent observation and 5...
Like other neoplasms, diffuse gliomas develop as a result of genetic and molecular alterations that further accumulate with tumor progression. These aberrations allow the tumor to acquire assets for sustained survival and growth and to escape normal growth restraining influences [39,40]. Some of these...
Regretfully, brain MRI showed evident progression of the intracranial lesion (Figure 1M-O). There was a solid enhancing lesion of high signal intensity on T2-weighted MR images, and low-intensity signals in the temporal area. The new lesion was thought to be a recur- rent tumor with ...
The expression of the matricellular protein periostin has been associated with glioma progression. In previous work we found an association of periostin wi... H Karin,C Zhu,C Ihsan,... - 《Journal of Neuropathology & Experimental Neurology》 被引量: 0发表: 2020年 Sox2-dependent maintenance of...
Additionally, the slow progression of the tumor indicates a low frequency of cycling. TmtmtiihmmeeeddeepisisIAIaannawwnndtiggidioeotteehnivhvntnteieceoecrrshrrhnaahaealleaolmlllm,l,uslsyoaauuloldt,lrrlthltvhvhbpepiiereevvaarantaaatspiielllpeeoyfionoynw,tf,ftttssfh7t7prh..reor33reeemooctct...
were progression-free survival (PFS) and overall survival (OS). The date of diagnosis was defined as the date of initial surgery and used as the starting date for PFS and OS, with survival measured until either tumor growth was noted on imaging follow-up, latest follow-up, or death. ...
Blockade of Notch signaling in tumor-bearing mice may lead to tumor regression, progression, or metastasis, depending on tumor cell types Neoplasia, 11 (2009), pp. 32-38 View PDFView articleView in ScopusGoogle Scholar 30 W Berger, S Spiegl-Kreinecker, J Buchroithner, L Elbling, C Pirker...