In this work, the authors report how the termination factor Sen1 interacts with an elongating RNA polymerase II (Pol II) and its nascent transcript to perform termination. Comparison of two pretermination states of Pol II supports a hypertranslocation model of termination. ...
In recent years, the number and types of known functional noncoding RNAs have increased considerably. A subset of both short- and long-sized species are known to be involved in thecisregulation of target genes located at or near the same genomic locus. Their expression is often coordinated wit...