NASH(non-alcoholic steatohepatitis),即非酒精性脂肪性肝炎,是由肝脏中脂肪堆积引起的肝脏疾病和炎症。根据流行病学数据,全球酒精性脂肪肝病(non-alcoholic fatty liver disease,NAFLD)发病率约25%,这些患者约有10-20%的可能进展为NASH,全球各地NASH发病率约为1.
非酒精性脂肪肝(Nonalcoholic Fatty Liver Disease,NAFLD)是指酒精和其它明确的损肝因素之外所致的肝细胞内脂肪过度沉积引发的代谢应激性肝脏损伤。非酒精性脂肪性肝炎(Nonalcoholic Steatohepatitis,NASH)是NAFLD进展而来的严重慢性肝脏疾病,流行病学数据显示,15%～25%的NAFLD患者最终会发展为NASH。 全球平均每3个人中就...
网络酒精无关的脂肪肝炎 网络释义 1. 酒精无关的脂肪肝炎 值得注意的是有一种与酒精无关的脂肪肝炎(nonalcoholic steatohepatitis-NASH),因为这种脂肪肝有15-50%的人有机会产生肝 … mypaper.pchome.com.tw|基于2个网页
NASH的英文全称是nonalcoholic steatohepatitis,中文释义是非酒精性脂肪肝炎。顾名思义,这种肝炎不是由酒精引起,而是因为脂肪太多。它归属于非酒精性脂肪性肝病,是其中的一种。后者的英文名称为nonalcoholic fatty liver disease,缩写为NAFLD。NAFLD以弥漫性脂肪浸润为特征,包括肝脏的单纯性脂肪变性(无炎症脂肪沉积)、非...
There are two types of non-alcoholic fatty liver disease: Non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH). 1.Alcoholic在上文中是"酒精"的形容词形式,但也可以作为名词来使用,指"酗酒的人"。 2.Steatohepatitis意为"脂肪肝...
2023年4月9日,安徽医科大学/南京医科大学孙倍成团队在Journal of Hepatology(If=30)在线发表了题为“A TNFα/Miz1-positive feedback loop inhibits mitophagy in hepatocytes and propagates nonalcoholic steatohepatitis”的研究论文,该研究发现在人类NASH中,Miz1的含量在肝细胞中减少。Miz1被证明与过氧化物还蛋白6...
Non-alcoholic fatty liver disease (NAFLD) includes a range of hepatic manifestations, starting with liver steatosis and potentially evolving towards non-alcoholic steatohepatitis (NASH), cirrhosis or even hepatocellular carcinoma. NAFLD is a major health burden, and its incidence is increasing worldwide...
Non-alcoholic steatohepatitis (NASH) is an important liver disease in children; it can cause cirrhosis in children. The disease mechanism involves hepatic ... Eve,A.,Roberts - 《Current Gastroenterology Reports》 被引量: 1032发表: 2007年 Non-alcoholic fatty liver disease (NAFLD) and the metaboli...
Nonalcoholic steatohepatitis (NASH), as a severe form of nonalcoholic fatty liver disease (NAFLD), is characterized by liver steatosis, inflammation, hepatocellular injury and different degrees of fibrosis. The pathogenesis of NASH is complex and multifa
When dosed therapeutically in a Stelic Mouse Animal Model of nonalcoholic steatohepatitis (NASH), PAT-505 treatment resulted in a small but significant ... G Bain,KE Shannon,F Huang,... - 《Journal of Pharmacology & Experimental Therapeutics》 被引量: 9发表: 2016年 Preclinical analysis of no...