SEXUAL DIMORPHISM IN CONSEQUENCES ON OFFSPRING Sex-related differences in heart and vascular function and in cardiovascular disease processes have been clearly demon- strated. Nevertheless, the precise mechanisms underlying these sex-related differences are poorly understood. Premeno- pausal women have ...
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The EGFR/lncRNA/ Foxp3 promoter (either wild type or mutant type) luciferase reporter vectors (pGL4 packaged) and the mock pGL4 vector were electroporated into 3 Â 106 CD4 þ T cells. After 24 h, cells were starved in serum-free medium and stimulated with Dynabeads Human T-...
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Testing for microsatellite instability (MSI) and DNA mismatch repair genes (MMR) are obligatory if the mentioned pre-selection criteria are rated positive. HNPCC syndrome is caused by an autosomal dominant genetic mutation in one of the four MMR genes—MLH1, MSH2, MSH6, PMS2. DNA repair ...
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