Non-HDL cholesterol (non-HDL-C) is a fraction that can be easily calculated from a traditional lipid panel. The value is strongly associated with an increased risk of heart disease. Over the years, LDL cholesterol (LDL-C) has been the most commonly used lipid variable to predict risk (1)...
Obicetrapib alone and in combination with ezetimibe reduces non-HDL-cholesterol by enhanced LDL-receptor-mediated VLDL clearance and increased net fecal sterol excretion in apoe*3-leiden.cetp micedoi:10.1016/j.atherosclerosis.2024.118435Jose Inia...
Conclusions: Obicetrapib alone and with ezetimibe reduced non-HDL-C levels by increased VLDL lipolysis, increased VLDL clearance and elevated LDL receptor levels, and enhanced fecal bile acid and neutral sterol excretion.Access through your organization Check access to the full text by signing in th...
TG、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL—C)、non—HDL-C、remnantcholesterol、AIP均较对照组升高,高密度脂蛋白胆固醇 (HDL—C)较对照组降低,且I组的remnantcholesterol、AIP均较II组升高。肥胖组儿童AIP与TG、non—HDL—C、reinnantch0les— terol呈正相关,与HDL—C呈负相关。37例行颈动脉超声检查的肥胖儿...
Abbreviations: AFLD, alcoholic fatty liver disease; ALT, alanine aminotransferase; CT, computerised tomography; HBV, steatosis due to hepatitis B virus; HCV, steatosis due to hepatitis C virus; HDLchol, HDL cholesterol; LDLchol, LDL cholesterol; waist, waist circumference; MetS, metabolic syndrome;...
HDL: High-density lipoproteins HmG-CoA: 3-Hydroxy-3-methylglutarylcoenzyme A HR-QOL: Health-related quality of life KCs: Kupffer cells LDL: Low-density lipoproteins LPS: Lipopolysaccharide LSECs: Liver sinusoidal endothelial cells LXR: Liver X receptor MetS: Metabolic syndrome NAFLD: ...
Although serum Cr and fasting blood glucose levels were non-significant between groups, NAFLD group members had significantly higher BPs and lipid profiles (LDL, VLDL, TG, and TC levels); ALT, AST, uric acid, and GGT levels; and lower HDL levels than non-NAFLD group members. Participants ...
Blood lipids such as serum activities of triglyceride (TG), total cholesterol (TC), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), and cholesterol (CHOL). 6. Other secondary outcome might include diamine oxidase (DAO), lipopolysaccharide, D-lactic acid...
Biochemistry measurements and evaluation of fatty liver Fasting blood samples were assessed by multichannel auto-analyzer for serum glucose, aspartate aminotrans- ferase (AST), alanine aminotransferase (ALT), total chol- esterol, triglyceride, HDL-cholesterol (HDL-C), and LDL-cholesterol (LDL-C)....
Baseline ratios of Tot-chol/HDL were elevated at 4.4–4.6 and there were no changes to these ratios after treatment (Figure 4), suggesting that the HDL-chol decrease was a consequence of decreased Tot-chol levels. ApoB also increased in the placebo group, consistent with elevation of LDL ...