FUMA GTEX v.8 tissue differentially expressed gene (DEG) analysis showed a significant 2-side association with blood (adj p = 3.5 × 10−3), heart (adj p = 8.0 × 10−3), and spleen (adj p = 9.2 × 10−3) (Table S6). Consistent with our previous analyses, FUMA implicates ...
Table 1supplementary shows the various Laboratory parameters for all participants. Of note that blood sugar was not poorly controlled at the time of biopsy. Also, male has worse renal function than females with worse GFR. Based on pathological...
Renal function impairment: Prostaglandins normally maintain renal blood flow by inducing vasodilation of the afferent arterioles. NSAIDS inhibit prostaglandin production, which leads to harmful hypoperfusion of the kidneys and reduced GFR. ; [6] Electrolyte and fluid abnormalities (edema, hyperkalemia, ...
Genomic DNA was extracted using the Blood & Cell Culture DNA Mini (<5 M cells) Kits (Qiagen, cat. no. 13323) as per the manufacturer’s instructions. To prepare samples for Illumina sequencing, a two-step PCR was performed to amplify the different regions of NEAT1. For each sample, ...
The lack of a decrease in nocturnal blood pressure is a risk factor for the progression of chronic kidney disease (CKD); however, it currently remains unknown whether it is a risk factor in normotensive CKD patients. We conducted a retrospective cohort s
Representative patterns Abbreviations HF: heart failure; LV: left ventricle; lncRNA: long noncoding RNA; PBMC: periph- eral blood mononuclear cells; TAC: mouse transverse aortic constriction; FFPE: formalin-fixed and paraffin-embedded; SNP: single nucleotide polymorphism; CAD: coronary artery diseases...
DNA was isolated from saliva in the study group and from umbilical cord blood in controls. Genotyping of polymorphisms was performed using quantitative PCR. There was no statistically significant association of IRF6 gene variants with NSCL/P occurrence, although for rs2013162, AA genotype, odds ...
Demographic characteristics, vascular risk factors, blood pressure at admission, and laboratory test indicators were compared among the four age groups of patients with NICE (Table 1). The findings revealed that, compared with G1, patients in G3 or G4 had a higher proportion of women, urban ...
The present study aimed to evaluate whether aortic hemodynamics (i.e., aSBP and CO) and cardiac contrac- tbilloitoyd(ip.er.e,sEsuesr)eca(bnrbDeBaPc)c,uhreaatertlyraptreed(HicRte)d, by the use of brachial systolic blood pressure (brSBP) and diastolic carotid-to-femoral pulse wave...
Complete blood count, glucose, lipids, liver enzymes, creatinine, high-sensitivity C-reactive protein (hs-CRP) and other biochemical blood parameters were measured using standard laboratory procedures at the Central Laboratory of the Verona Integrated University Hospital, using relative reference techniques...