A double-blind study conducted at Duke University Medical Center used nicotine patches to see if it would improve attentiveness in non-smoking adults without attention deficits. Subjects received 7 mg of nicotine per day using a transdermal patch for a 4 ½ hour morning session. Nicotine signific...
As evidence of successful nico- tine dependence induction, weight gain during withdrawal, occurrence of somatic withdrawal signs and nicotine as well as cotinine blood levels were assessed in the patch exposed and control rats. The nicotine dependence induction following chronic application of nicotine ...