Another family of transcription factors whose members are constitutively activated in many human tumors is the STAT family. These proteins can control various cellular events such as proliferation, differentiation and cell survival [11]. One member in particular...
Carpesium Macrocephalum Attenuates Lipopolysaccharide-Induced Inflammation In Macrophages By Regulating The NF-kappa B/i Kappa B-alpha, Akt, And Stat Signaling Pathways 作者: Kim, Tack-Joong;Lee, Kwang-Ho;Shim, Do-Wan;Kang, Tae-Bong;Koppula, Sushruta;Kim, Wan-Jae;Oh, Na-Hyun;Jiang, Jun;...
The Janus Kinase (JAK) and signal transduction and activator of transcription factor 3 (STAT3) pathway is required for full activation of the NF-κB pathway and its main stimulator is IL-6. The IL-6 when binds to its receptor activates JAK-STAT pathway allows phosphorylated STAT3 to translocat...
NF-κB (核因子活化B细胞κ轻链增强子)是调控DNA转录的蛋白复合物,存在于几乎所有类型的动物细胞中,参与细胞对刺激物(如压力、细胞因子、自由基、紫外辐射、氧化低密度脂蛋白、细菌或病毒抗原等)产生应答。最近发现NF-κB与癌症、炎症、自身免疫疾病、感染性休克、病毒干扰和不合适的免疫发育相关。因此NF-κB可作为药...
YK175一抗Stat5a浓缩液0.1ml900进口分装 YK176一抗Survivin浓缩液0.1ml1000进口分装 YK177一抗Surfacant Protein A(100-200)浓缩液0.1ml1400进口分装 YK179一抗Synaptophysin 突触素浓缩液0.1ml900进口分装 YK180一抗tau浓缩液0.1ml900进口分装 YK181一抗TdT 末端脱氧核苷酸转移酶浓缩液0.1ml900进口分装 ...
Whether the disfunction of RELA induced a change in the STAT pathway or AGP directly acted on STAT, remains unclear. Based on the results of the analysis of 653 DEGs, NF-κB pathway related genes were selected for further research. The expression of CD40 and TRAF1 genes was clearly ...
关键词: AIDS/HIV NL4-3 IIIB T lymphocyte signal transduction JAK3 STAT5 DOI: 10.1006/viro.2001.0999 被引量: 31 年份: 2001 收藏 引用 批量引用 报错 分享 全部来源 免费下载 求助全文 全文购买 Elsevier 国家科技图书文献中心 (权威机构) 万方医学 万方医学 掌桥科研 查看更多 相似文献 参考文献 引证...
Binding of cytokines to their receptors on the beta-cells activates MAP-kinases and the transcription factors STAT-1 and NFkappa-B, provoking functional ... Pierre,Pirot,Alessandra,... - 《Arquivos Brasileiros De Endocrinologia E Metabologia》 被引量: 170发表: 2008年 ...
[13] Khorooshi R,Babcock AA,Owens T.NF-kappaB-driven STAT2and CCL2expression in astrocytes in response to brain injury[J].J Immunol,2008,181(10):7 284-7 291. [14] Anderson KJ,Scheff SW,Miller KM,et al.The phosphorylated axonal form of the neurofilament subunit NF-H(pNF-H)as a bl...