NLRP3 gene knockout blocks nf-kappa B and MAPK signaling pathway in CUMS-induced depression mouse model. Su,W.J,Zhang,Y,Chen,Y,Gong,H,Lian,Y.J,Peng,W,Liu,Y.Z,Wang,Y.X,You,Z.L,Feng,S J.et al. Behavioural Brain Research . 2017...
Small interfering RNA (siRNA) knockdown shows that NLRP3 inammasomes, but not NLRC4, participate in fullerenol-induced IL-1β production. Potassium efflux, activation of P2X7 receptor and intracellular reactive oxygen speciesare also important factors required for fullerenols-induced IL-1β release...
The expression of NS5ATP9 and activities of transforming growth factor-beta 1 (TGF beta 1)/Sekelsky mothers against decapentaplegic homolog 3 (Smad3) and NF-kappa B/NOD-like receptor pyrin domain containing 3 (NLRP3) inflammasome signaling pathways were detected in TAF/TDF-treated mice and LX-...
Therapeutic effects of silibinin on LPS-induced acute lung injury by inhibiting NLRP3 and NF-kappa B signaling pathwaysSilibinin Wang,Tan,Tian,... - 《Microbial Pathogenesis》 被引量: 0发表: 2017年 α-Asarone attenuates microglia-mediated neuroinflammation by inhibiting NF kappa B activation and ...
1. Baicalin suppresses NLRP3 inflammasome and nuclear factor-kappa B (NF-κB) signaling during Haemophilus parasuis infection [J] . Shulin Fu, Lei Xu, Sali Li, Veterinary research . 2016,第1期 机译:黄ical苷抑制副猪嗜血杆菌感染期间的NLRP3炎性体和核因子-κB(NF-κB)信号传导 2. Baical...
Complement Membrane Attack Complexes Assemble NLRP3 Inflammasomes Triggering IL-1 Activation of IFN-gamma-Primed Human Endothelium Rationale: Complement activation contributes to multiple immune-mediated pathologies. In late allograft failure, donor-specific antibody deposits complemen... Xie, Catherine B.Qin...
Inhibition of TRIM14 protects cerebral ischemia/reperfusion injury through regulating NF-κB/NLRP3 pathway-mediated inflammation and apoptosis Purpose Many proteins in tripartite motif (TRIM) family have been reported to play an important role in cerebral ischemia/reperfusion (I/R) injury. This st.....
Beyaert, Karin and colleagues discuss the key molecular mechanisms that contribute to the self-limiting nature of inflammatory signaling, with emphasis on the negative regulation of the NF-[kappa]B pathway and the NLRP3 inflammasome.doi:10.1038/ni.3772Inna S Afonina...
Conclusion: USP 1 exhibits protective role in MC3T3-E 1 cells by suppressing NF-kappa B-NLRP3 mediated pyroptosis in response to H2O2 The involvement of USPI and TRAF6 in NLRP3 inflammasome signaling suggests a future therapeutic potential to improve clinical symptoms in osteoporosis.Sun, Dengshuo...
NaB inhibited the phosphorylation of NF-kappa B and activation of NLRP3 inflammasomes, and reduced the secretion of corresponding inflammatory factors. Furthermore, NaB promoted the occurrence of mitophagy via activating the expression of Pink1/Parkin.Conclusions In conclusion, our results indicate that ...