NIK- and IKKβ-binding protein promotes colon cancer metastasis by activating the classical NF- κB pathway and MMPs [J ] .Tumor Biol, 2016( 5 ) : 1-12.Qin M, Liu S, Li A, Xu C, Tan L, Huang J, Liu S. NIK- and IKKβ-binding pro- tein promotes colon cancer metastasis by ...
摘要: Polysaccharides derived from Inonotus obliquus (PI 关键词:Inonotus obliquus B16-F10 melanoma cell migration invasion MMPs NF-kappa B 年份: 2014 收藏 引用 批量引用 报错 分享 全部来源 求助全文 国家科技图书文献中心 (权威机构) 相似文献 参考文献...
Differential regulation of MMPs by E2F1, Sp1 and NF-kappa B controls the small cell lung cancer invasive phenotype. BMC Cancer. 2014; 14 :276.Li Z, Guo Y,Jiang H, et al. Differential regulation of MMPs by E2F1, Sp1 and NF-kappa B controls the small cell lung cancer invasive phenotype...
Then it increased the level of TNF-alpha and the expression of MMPs, which induce the degradation of ECM and accelerated skin aging. We also summarize some reported natural antioxidants and synthetic antioxidants which are related to NF-kappa B signals. On the other hand, NF-kappa B plays a...
The levels of matrix metalloproteinases (MMPs), ADAMTS, Bax, and Bcl-2 were measured by PCR, ELISA, and Western blotting. Caspase-3 activity in chondrocytes was determined using a caspase-3 activity assay. Western blotting was also performed to examine activation of the NF-κB...
Elevated production of angiogenic molecules (VEGFs, CEACAM and MMPs) in filarial pathology has been shown to be dependent on phosphorylation and intracellular activation of NF-κB. This review examines the role of NF-κB in filarial pathology and its potential therapeutic options for individuals ...
Inhibiting cytokines alleviates induction of MMPs in resident skin cells, and also alleviates inflammation with its concommitant induction of neutrophils from the blood stream bringing MMPs and elastase into the acne lesion. Dimishing the presence of matrix-degrading enzymes in the acne lesion reduces...
the inflammatory reaction leading to macrophage-derived proinflammatory cytokines, such as IL-1[beta], IL-6, IL-8 and TNF-[alpha], that promote inflammation, neovascularization and cartilage degradation via activation of matrix-degrading enzymes, such as ma...
NF-kappa B signaling plays an important role in regulating MMPs gene expression and involves in OA pathogenesis. Post-traumatic arthritis (PTA) is secondary to joint injury. However, the role of NF-kappa B in PTA pathogenesis remains unclear. This study established rat PTA model, on which the...
The aim of this study was to investigate the effects of doxycycline on the expression of MMPs in lipopolysaccharide (LPS)-induced PC3 human prostate cancer cells and the possible role of NF-kappa B signaling.Ogut, DenizReel, BuketKorkmaz, Ceren GonenArun, Mehmet ZuhuriMicili, Serap Cilaker...