Overexpression of nerve growth factor (NGF), brain derived neurotrophic factor (BDNF), and glial derived neurotrophic factor (GDNF) provide additional growth signals for nerves. Increased density of nerves and thickness of nerve bundles has been observed histologically in pancreatic ductal adenocarcinoma....
Brain-derived neurotrophic factor (BDNF)InflammationNeurotoxicity NFNF- <kappa >B pathwayVenenum BufonisEthnopharmacological relevance: Venenum Bufonis (VB), also called toad venom, has been widely used in clinic as a cardiotonic, anohyne and antineoplastic agents both in China and other Asian ...
Furthermore, the administrations of GEN ameliorated the alterations of BTK, TLR4, MyD88, NF-kappa B, and BDNF in HFD + STZ-induced mice. With the application of ibrutinib, the selective inhibitor of BTK, it was also found that BTK/TLR4/NF-kappa B pathway was associated with the GEN ...
Gene expression analysis was performed using control hAFSCs (not treated, “Ctrl”) and neuronal differentiation-induced hAFSCs (treated for 5 days with 50 ng/mL BDNF + 100 ng/mL NGF + 5 mM KCl + 2 μM RA; denoted as “Neuro”). Control and neuro-induced hAFSCs were cultivated ...
Standardized extract of Glehnia Littoralis abrogates memory impairment and neuroinflammation by regulation of CREB/BDNF and NF-κB/MAPK signaling in scopolamine-induced amnesic mice model. Biomed. Pharmacother. 2023, 165, 115106. [Google Scholar] [CrossRef] Amor, S.; Puentes, F.; Baker, D.; ...
Ethanol extract of Oldenlandia diffusa herba attenuates scopolamine-induced cognitive impairments in mice via activation of BDNF, P-CREB and inhibition of acetylcholinesterase. Int. J. Mol. Sci. 2018, 19, 363. [Google Scholar] [CrossRef] [PubMed] Disclaimer/Publisher’s Note: The statements, ...