Ewing sarcoma, a member of the Ewing sarcoma family of tumors which also include primitive neuroectodermal tumor and Askin tumor, is the second most common variety of primary bone cancer of childhood. The survival rate for localized Ewing sarcoma has substantially improved over the last three ...
IFN-γ + TNF-α could be a new approach for Ewing’s sarcoma. Inpharma Wkly. 908, 12 (1993). https://doi.org/10.2165/00128413-199309080-00024 Download citation Published15 February 2013 Issue DateOctober 1993 DOIhttps://doi.org/10.2165/00128413-199309080-00024 Keywords Sarcoma Interferon Inhi...
synthesis and release and promoting vasculogenic mimicry in hypoxic conditions, substantiates its involvement in angiogenesis and subsequent upregulation in angiogenically stimulated cells [18]. Survivin also binds to c-Src (cellular sarcoma) establishing a bidirectional relationship that adversely ...
"Ewingsarcomais almost always caused by acancer-causing protein called EWS/FLI," said Stephen Lessnick, M.D., Ph.D., director of HCI's Center for Children'sCancer Research, professor in the Department of Pediatrics at the University of Utah School of Medicine, and an HCI investigator. In...
Ewing's sarcoma is a bone cancer commonly diagnosed in about 250 U.S. teenagers per year. If early chemotherapy is effective, improvement can be durable. But for children and teens who respond poorly to a first attempt at chemotherapy or if the disease s
在癌症的世界里,尤因肉瘤(Ewing sarcoma,ES)如同一个凶狠的 “恶魔”,它主要在儿童和年轻人中肆虐,是一种侵袭性很强的骨癌。其背后的 “罪魁祸首” 是致癌融合蛋白 EWSR1::FLI1,这个特殊的蛋白在正常细胞中不见踪影,所以成为了极具吸引力的治疗靶点。然而,它就像一个 “狡猾的对手”,作为转录因子,缺乏酶活性...
Cabozantinib demonstrated antitumor activity as treatment of patients with advanced Ewing sarcoma and osteosarcoma, warranting further investigation for a potential new therapeutic option for this patient population, according to findings from phase II C
本研究报告一例33岁女性右面部肿胀6个月的罕见病例,经诊断为头颈部骨外尤文肉瘤(Extraskeletal Ewing's Sarcoma)。研究人员通过该病例强调,此类与口腔鳞癌(OSCC)表现相似的软组织肿瘤需纳入鉴别诊断,填补了头颈部区域该肿瘤类型文献报道的空白,为耳鼻喉科及头颈肿瘤科医师提供了重要临床参考。
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