Parkinson's disease (PD) is the most common neurodegenerative movement disorder. Recent advances in genetics and pathophysiology have led to new insights into the pathogenesis of PD. Ten loci have been linked to hereditary PD. Mutations in 伪-synuclein and ubiquitin carboxy hydrolase L1 (UchL1) ...
Parkinson’s disease remains one of the most feared neurodegenerative conditions. DDW’sMegan Thomasreports on the latest clinical progress as pharma and biotech search for new therapies for this currently incurable condition.
Public information shows that this is Opicapone capsule, a new drug introduced by Fosun Pharma for the treatment of primary Parkinson's disease, which is a next-generation catechol oxygen methyltransferase inhibitor (COMT). Public information shows that opicapone is a new generation of peripheral cate...
Studies indicating that smokers appear less likely to develop Parkinson's disease and suggesting that pesticides increase the risk of the disease; Experiment in a gene therapy treatment for Alzheimer's disease.WeberWimLancet
By following a group of newly diagnosed patients with Parkinson's disease (PD) for a decade or more, researchers have been able to identify several factors never before reported that appear to be associated with higher mortality rates in PD patients comp
Parkinson's disease, characterized by various motor dysfunctions, is the second most common neurodegenerative disorder in the world. It is known that specific gene mutations that are passed down through families are responsible for some cases of Parkinso
Allen WA.doi:10.1038/sj.bdj.4807300AllenW ABritish Dental Journal
Idiopathic Parkinson's disease (IPD) is the second most common neurodegenerative disorder after Alzheimer's disease. Treatment aims in IPD include the provision of symptomatic relief reduction of functional disability, halting or slowing of the neurodegenerative process, and the prevention of long-term ...
Multiple factors have been hypothesized over the last century to be causative or contributory for Parkinson's disease. Hereditary factors have recently emerged as a major focus of Parkinson's disease research. Until recently most of the research on the etiology of Parkinson's disease concentrated on...
Parkinson's disease (PD) is an idiopathic disease and its pathological feature is a loss of pigmented neurons in the substantia nigra. Some commonly used pesticides possess neurotoxicity, and exposure to such compounds may trigger mechanisms similar to those in the development of idiopathic PD. We...