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Amyotrophic lateral sclerosis (ALS) is a fatal disease. As its pathological mechanisms are not well understood, there are no efficient therapeutics for it at present. While it is highly heterogenous both etiologically and clinically, it has a common salient hallmark, i.e., aberrant protein aggreg...
(Ref.93); hence, IL-33 could provide a link between CNS injury and activation of IL-4 production. An IL-33-responsive population of tissue-resident regulatory T cells has been identified in the muscle94,95and gut of mice96, and contributes to resolution of inflammation and wound repair in...