Regulation of neural gene transcription by optogenetic inhibition of the RE1-silencing transcription factor. Proc Natl Acad Sci USA. 2016;113:E91–100. Article CAS PubMed Google Scholar Hogg SJ, Motorna O, Cluse LA, Johanson TM, Coughlan HD, Raviram R, et al. Targeting histone acetylation ...
(2017) Lysine Acetylome Analysis Reveals Photosystem II Manganese-stabilizing Protein Acetylation is Involved in Negative Regulation of Oxygen Evolution in Model Cyanobacterium Synechococcus sp. PCC 7002. Molecular & Cellular Proteomics 16, 1297-1311...
2.1.1. Regulation of tra Gene Expression The ability of the donor strain to perform conjugation requires the expression of the transfer genes clustered in the tra region of the plasmid. The transfer genes encode all the protein factors involved in the elaboration of the conjugative pilus and the...
xenografts. Analysis of the menin interactome suggests that menin could drive TNBC tumorigenesis through the regulation of MLL/KMT2A-driven transcriptional activity, mRNA 3′-end processing and apoptosis. The study provides a rationale behind the use of ASO-based therapy, targeting menin in ...
2.2.3. Protein Expression in 7HF-Treated Cells The results of the proteomic and STRING analyses were generally representative of G2/M cell cycle protein expression, which involved the regulation of G2/M-phase transition, mitotic chromosome segregation, mitotic spindle organization and mitotic checkpoi...
Recent insights into the TNBC complexity have been explained by epigenetic regulation and its ability to alter specific oncogenes and tumor suppressor genes. It has opened an emerging area in anti-cancer targeted therapy using epigenetic modulators [11]. The epigenetic drugs are synthetic or natural...