Espat NJ (2007) Is there an increased negative outcome for hepatic resection following pre-operative chemotherapy? World J Surg 31:365–366
Single agent is preferable to combination chemotherapy, and longer planned duration improves outcome but must be balanced against toxicity. There is no single optimal first-line or subsequent line chemotherapy, and choice of treatment will be determined by multiple factors including prior therapy, ...
The role of platinum-based chemotherapy (PBCT) in the treatment of triple-negative breast cancer (TNBC) is still undetermined. The aim of this study was to compare the efficacy of PBCT versus non-PBCT in patients with lung metastasis from TNBC. Clinical data on patients diagnosed and treated ...
.044;P=.049),specificallyamongpatientstreatedwithadjuvantchemotherapy.WeconcludethatALDH1 associateswithderegulatedβ-cateninsignaling,supportingtheroleofALDH1inrectalcancerstemness. ALDH1expressionrelatestopooroutcomeinearlystagerectalcancer,agroupwherenewprognostictools ...
To reduce bias, patients were subdivided into three groups: those who were recommended chemotherapy but did not receive it; those who received chemotherapy; and those for whom chemotherapy was not recommended and not given. The primary outcome was overall survival. Multivariate Cox regression analysis...
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin. Nature 547, 99–103 (2017). Article ADS CAS PubMed Google Scholar Ouyang, B. et al. Albumin-based formononetin nanomedicines for lung injury and fibrosis therapy via blocking macrophage pyroptosis. Mater. Today Bio...
These results suggest that increased MCL-1 expression protects TNBCs from chemotherapy-induced apoptosis38. Our results suggest that homoharringtonine may similarly reduce the levels of MCL-1 and sensitize TNBC cells to the cytotoxic agent paclitaxel. The strong synergy observed for the homo...
Further, we demonstrate that nitrofen its analogues, are very effective in reversing mesenchymal phenotype to a more epithelial-like phenotype. This may be significant for the treatment of patients with mesenchymal-TNBC tumor subtype who are well known to exhibit high resistance to chemotherapy....
Triple-negative breast cancer (TNBC), a highly aggressive subtype of breast cancer, negatively expresses estrogen receptor, progesterone receptor, and the human epidermal growth factor receptor 2 (HER2). Although chemotherapy is the main form of treatmen
- 《Antimicrobial Agents & Chemotherapy》 被引量: 346发表: 1995年 Impact of Antibiotic MIC on Infection Outcome in Patients with Susceptible Gram-Negative Bacteria: a Systematic Review and Meta-Analysis The objective of this study was to analyze the impact of MIC values within the susceptible ...