the inducer-responder relationships are different in the two cancer subtypes; (3) key neural functions such as neural crest formation are predicted to enhance adaptive immunity in TNBC while glia development, a
1. Introduction 2. HIF-1α expression in the TNBC 3. HIF-1α regulates the progression of TNBC 4. Combined application of targeted HIF-1α for chemotherapy, immunotherapy and anti-angiogenic therapy, and PDT 5. Potential drugs targeting HIF-1α 6. Conclusions and future directions CRediT auth...
The Complement and HRP Conjugate (REVEAL-Biotin-Free Polyvalent DAB-Spring Bioscience, Pleasanton, CA) were applied, followed by the chromogenic substrate (DAB) and Harris Hematoxylin. The assembly of the slides was performed in 50% glycerol and sealed. All immunoreactions were accompanied by a ...
Tumor volume was measured two to three times a week with a caliper, and tumor volume was calculated using the formula V = (a2*b)/2, where b is the longest axis and a is the perpendicular axis to b. Depending on the model used, primary tumors, lungs, livers, and spleens were ...
Biomass is often assigned a central role in future energy system scenarios as a carbon sink, making negative greenhouse gas emissions possible through carbon capture and storage of biogenic carbon dioxide from biomass-fuelled power plants. However, biomass could also serve as a strategic complement to...
To define the possible regulation of IRE1α by BI-1, we determined the levels of xbp-1 mRNA splicing using two different methods in BI-1 knockout (BI-1 KO) murine embryonic fibroblasts (MEFs). We titrated down the dose of the experimental ER stressor tunicamycin (Tm) to a point at ...