The active and passive mobility of the upper thoracic spinal segments should be evaluated and treated with the cervical spine. Table 6-6 shows that the upper thoracic spine (T1–T6) provides approximately 25% of the cervical flexion/extension, 10% of the cervical rotation, and 14% of the ...
Accurate organ-at-risk (OAR) segmentation is critical to reduce radiotherapy complications. Consensus guidelines recommend delineating over 40 OARs in the head-and-neck (H&N). However, prohibitive labor costs cause most institutions to delineate a su
Sentinel lymph node biopsy for oral cavity lesions has been evaluated. Forty patients with clinically N0 neck cancer underwent sentinel lymph node biopsy followed by complete neck dissection. A sentinel node was identified in 90% of necks, with a 97% accuracy rate in predicting the nodal status ...
The clinical parameters included tumor site, tumor size (pT), lymph node metastases (pN), histopathological grade, and UICC stage. The genetic parameters consisted of a comprehensive set of chromosomal alterations determined by CGH corresponding to the 400-band ISCN nomenclature. All noninformative ...
Head and neck squamous carcinoma (HNSCC) is known for its high aggressiveness and susceptibility to cervical lymph node metastasis, which greatly contributes to its poor prognosis. During tumorigenesis, many types of cancer cells acquire oncogenic super-enhancers (SEs) that drive the overexpression of...
The influence of lymph node metastasis in the treatment of squamous cell carcinoma of the oral cavity, oropharynx, larynx, and hypopharynx: N0 versus N+. Objectives/Hypothesis: Management of the N0 neck is a continuing controversy. The study compares the influence of N0 and N+ disease on the...
Gregoire V, Coche E, Cosnard G et al (2000) Selection and delineation of lymph node target volumes in head and neck conformal radiotherapy. Proposal fo... Ricardo,Cendales,Luis,... - 《Clinical & Translational Oncology》 被引量: 22发表: 2011年 [Target volume delineation for head and neck...
includes the region encoding the Fas-associated death domain gene (FADD; established as frequently overexpressed in HNSCC [117] and found to be amplified in 32 % of HPV- cases analyzed by the TCGA [19]). Importantly, FADD has been implicated in increased lymph node metastasis in HNSCC [117...
There are four independent predictors of cancer recurrence, including positive surgical margin (HR = 1.63), advanced cancer stage (HR = 1.59), lymph node involvement (HR = 1.96), and adjunct radiotherapy (HR = 0.61) (Table 3) after multivariate analysis. The association of perioperative ...
Moreover, the diagnosis of cervical lymph node metastasis is a necessary condition for clinical staging and treatment, which is also an essential factor affecting the prognosis of HNSCC [36,115,116,117]. However, the accurate diagnosis of lymph node metastasis still has limitations. Patients with...