TM1 and TM6 form the gating bundle, and the sliding of this two-helix cluster was suggested to be a major conformational change associated with the alternating-access during the transport cycle turnover [24]. This hypothesis is strongly supported by the X-ray structures of the H+/Ca2+ (...
The cost-of-living crisis has created a lot of pressure for our people and in addition to the energy support payments and package improvements in 2022, we officially recognised that we were paying our people the real living wage by signing up to the Real Living Wage Foundation in 2023. Our...