Although most meningiomas have a good long-term prognosis after treatment, there are still controversies over their management in a subset of cases. While surgery is the first-line treatment, the use of fractionated radiotherapy or stereotactic radiosurgery is indicated for residual or recurrent tumors...
Review the data published on the subject to create a more comprehensive natural history of intraventricular meningiomas (IVMs). A Medline search up to March 2018 using “intraventricular meningioma” returned 98 papers. As a first selection step, we adopted the following inclusion criteria: series an...
The FDA recently approved an antisense drug, VITRAVENE™ (for treatment of cytomegalovirus retinitis), reflecting that antisense has therapeutic utility.SUMMARYIn one embodiment, the invention provides methods for inhibiting the action of a natural antisense transcript by using antisense oligonucleotide(s...
We discuss the differential diagnosis between chordoma, chordoid meningioma, germinoma and pituitary adenoma. Histologically, the tumour showed cords and lobules... JR Ricoy,RD Lobato,B Báez,... - 《Acta Neuropathologica》 被引量: 106发表: 2000年 Detection of specific genetic abnormalities by ...
Through years of evolutionary selection pressures, organisms have developed potent toxins that coincidentally have marked antineoplastic activity. These natural products have been vital for the development of multiagent treatment regimens currently employed in cancer chemotherapy, and are used in the treatment...
Treatment options and predictive factors for recurrence and cancer-specific mortality in bladder cancer after renal transplantation: A multi-institutional ... CONCLUSIONS: Adjuvant bacillus Calmette-Gurin signicantly reduces the risk of recurrence, as does switch to mTOR inhibitors. Multiple tumors increas...
In addition, radiosurgery plays a role in the treatment of meningiomas as a primary treatment modality, or as a salvage therapy. Decisions regarding management should be made with an understanding of the natural history and rate of growth. In this chapter we review the known meningioma ...
Selection for further treatment and follow-up strategy may benefit from knowledge of volumetric growth and associated prognostic factors. MATERIAL AND METHODS. Growth rates were assessed using a linear mixed effects model, in a retrospective adult cohort that underwent subtotal resection of meningioma (...
The nanoparticles (NPs) approach provides the platform for gene therapy, treatment, diagnosis and monitoring the response. The blood-brain barrier (BBB) is mainly tight junctions present between the brain endothelial cells that mainly control the flow of nutrients, ions, cells towards the brain [...
Primary acute myeloid leukemia (AML) cells have a higher expression of AC, which is essential for AML blast survival. In AML cell lines, increased levels of AC induced a higher expression of antiapoptotic Mcl-1 protein, increased S1P, and decreased Cer. Treatment with the AC inhibitor, LCL204...