Nanosponge-based delivery systems have been applied for cancer therapy with high specificity, biocompatibility, degradability, and prolonged release behavior. In this context, the drug loading within nanosponges is influenced by the crystallization degree. Notably, 3D printing technologies can ...
INTRODUCTION: The design of new nanocarriers as a strategy for the delivery of anti-cancer drugs offers a potential platform to overcome some limitations of current clinical treatments and to achieve targeted release into tumour tissues. Cyclodextrin-based nanosponges are a novel nanosized delivery sys...
Here, we generated SL-loaded glutathione/pH-responsive nanosponges (GSH/pH-NS) to selectively deliver SLs to prostate cancer cells and enhance their therapeutic efficacy. The SLs were readily incorporated into the GSH/pH-NS. The drug loading efficiency was 13.9% for MEB55 and 15.4% for ST362...
Thermoresistance shields cancer cells from damage by hyperthermia, decreasing the efficacy of photothermal therapy. Therefore, the design of photothermal therapeutic systems that avoid inducing thermoresistance is highly desirable for precision medicine. Herein, by simply assembling a cationic polymer and a...
drug deliveryglutathione-responsive polymersnanospongesCyclodextrin-based nanosponges are designed as new nanostructured material for drug delivery. Invitro and invivo studies show that nanosponges can increase the effectiveness of anti-cancer drugs encapsulated within their nanostructure. Reported is a new,...
Cyclodextrin-based nanosponges in drug delivery and cancer therapeuticsdoi:10.1016/B978-0-12-813741-3.00005-4Riyaz Ali M. OsmaniParthasarathi K. KulkarniVishakante GowdaUmme HaniChandani Saha
Cyclodextrin-based nanosponges are designed as new nanostructured material for drug delivery. Invitro and invivo studies show that nanosponges can increase the effectiveness of anti-cancer drugs encapsulated within their nanostructure. Reported is a new, cheap glutathione (GSH)-responsive material easily...
The application of nanosponges to cancer drug delivery. Expert Opin. Drug Deliv. 2014, 11, 931–941. [CrossRef] [PubMed] 8. Swaminathan, S.; Cavalli, R.; Trotta, F. Cyclodextrin-based nanosponges: A versatile platform for cancer nanotherapeutics development. Wiley Interdiscip. Rev. Nanomed...
Among the different molecules that have been studied in the context of their potential anti-tumor effects, polyphenols and nitrogen mustards have shown to be effective against various types of tumor cell lines, such as lung, multiple myeloma, ovarian, breast and gastric cancer, among others [18...
Thus, nanosponges are effective carrier for the delivery of actives and developed as a commercial drug delivery system in pharmaceutical industries after certified clinical studies. In the near future, beta-CDNS-based product will capture the market due to its diverse applications in anti-cancer, ...