It has long been assumed that mycoplasmas exist only on the outside of the eukaryocytic cell membrane (cytadherence). However, recent studies have demonstrated the intracellular location of certain mollicutes (M.fermentans, M. genitaliumandM. pneumoniae), not only afterphagocytosisby granulocytes ...
Although previously classified as Haemobartonella and Eperythrozoon spp., sequence analysis of the 16S rRNA genes of these organisms has shown that they are closely related to the pneumoniae group of mycoplasmas, which includes the human mycoplasmal pathogens Mycoplasma pneumoniae and Mycoplasma ...
Mycoplasma pneumoniae(MP) is a leading pathogen of respiratory infection, especially community-acquired pneumonia (CAP), in children worldwide. However, its diagnosis is frequently ineffective because bacterial culture and serology test are usually positive 1–2 weeks or more after the disease onset. ...
One of the many compounds known to activate the NRF2 pathway is hydrogen peroxide33. The production of hydrogen peroxide was previously described to have an important cytotoxic effect in severalMycoplasmaspecies, such asM. pneumoniae34andM. mycoidessubsp.mycoides35. More specifically, the cytotoxity o...
Mycoplasma ovipneumoniae (M. ovipneumoniae) is a significant pathogen causing respiratory infections in goats and sheep. This study focuses on investigating vulnerability of Hu sheep to M. ovipneumoniae infection in the context of late spring’s cold wea
Chamydophila pneumoniae (CP) and/or Mycoplasma pneumoniae (MP) are two bacteria detected in vulnerable atheromas. In this study we aimed to analyze whether CP and/or MP aggravates atherosclerosis induced by cholesterol-enriched diet in C57BL/6 apoE KO male mice. Thirty male apoE KO mice aged...
Acute respiratory tract infections (ARIs) are common and frequently-occurring diseases in childhood. Pneumonia is responsible for 260,000 deaths in children each year in China (1).Mycoplasma pneumoniae(MP) is one of the main pathogens associated with ARIs in children. Notably, ~40% of patients ...
Usuallyspherical,doublespherical,filamentousVegetativemode:binaryfissionStain:hardtobestainedinGram.Giemsa,blueM.PneumoniaewithGiemsastainStructure(Underelectronmicroscope)Threelayers:outerandinnerlayerscontainproteinandglycogen,meddlelayeriscomposedoflipid(cholesteroltakesup36%)Theonlycellularorgan–ribosome.DNAandRNA,gene...
The virus particles under the electron microscope appeared as spheres or long strips connected by several particles, revealing a complete viral membrane structure composed of virus lipid bilayer, hemagglutinin, neuraminidase, and matrix proteins. Conclusion: The recombinant viruses rFLU‐P1a ...
All HMs form a single cluster within the ‘pneumoniae’ group, with Mycoplasma fastidiosum as the closest relative (Rikihisa et al., 1997; Neimark et al., 2001; Peters et al., 2008). However, the unique biological characteristics of HMs (mainly tropism for RBCs), in conjunction with the...