doi:10.3390/diagnostics13040766CANCER diagnosisMOLECULAR diagnosisCANCER prognosisTUMOR markersNUCLEIC acidsCancer is a complicated disease. Globally, it is one of the major causes for morbidity and mortality. A critical challenge associated with it is the difficulty to accurately diagn...
Contemporary molecular tests for prognosis and treatment guidance for castration-resistant prostate cancer. Expert Rev Mol Diagn 2016;16:1113-20.Buonerba C,... C Buonerba,Di Lorenzo, Giuseppe,G Sonpavde - 《Expert Review of Molecular Diagnostics》 被引量: 6发表: 2016年 Molecular biomarkers in...
Molecular biomarkers for an early diagnosis, effective treatment and prognosis of colorectal cancer: Current updates Colorectal cancer (CRC) is the third most prevalent cancer in the world. Globally, it has been estimated that about 1.4 million new cases of colorectal can... A Mahasneh,F Al-Sh...
国际期刊Frontiers in Molecular Biosciences(最新影响因子4.188)”Molecular Diagnostics and Therapeutics” 栏目正在征稿,研究主题“Molecular Biomarkers for the Diagnosis, Prognosis, and Risk Prediction of Cancer(癌症诊断、预后和风险预测的...
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic...
and the rate of the approval of targeted cancer therapies remains woefully low. A key challenge and priority in cancer research is therefore to identify molecular biomarkers that could be used to improve early diagnosis, as well as to guide prognosis and the design and monitoring of new therapeut...
childhood haematological malignanciesgene expressionmolecular diagnosticstelomeremathematical modellingSummary We have prospectively analysed and correlated the gene ... FWV Delft,T Bellotti,Z Luo,... - 《Br J Haematol》 被引量: 30发表: 2015年 Individualised cancer therapeutics: dream or reality? Establis...
Karina Dalsgaard Sørensen,Torben Falck Ørntoft - 《Expert Review of Molecular Diagnostics》 被引量: 124发表: 2010年 Estrone sulfate (E1S), a prognosis marker for tumor aggressiveness in prostate cancer (PCa) Seeking insight into the possible role of estrogens in prostate cancer (PCa) evolutio...
The number of druggable tumor-specific molecular aberrations has grown substantially in the past decade, with a significant survival benefit obtained from biomarker matching therapies in several cancer types. Molecular pathology has therefore become fund
A key challenge and priority in cancer research is therefore to identify molecular biomarkers that could be used to improve early diagnosis, as well as to guide prognosis and the design and monitoring of new therapeutic avenues. This Insight highlights key approaches for the discovery and validation...