Peptide motif of the cattle MHC class I antigen BoLA-A11. Immunogenetics 1995;42:302±3.Hegde NR, Ellis SA, Gaddum RM, Tregaskes CA, Sarath G, Srikumaran S (1995) Peptide motif of the cattle MHC class I antigen BoLA-A11. Immunogenetics 42:302-303...
The identity of histocompatibility loci, besides human leukocyte antigen (HLA), remains elusive. The major histocompatibility complex (MHC) class IMICAgene is a candidate histocompatibility locus. Here, we investigate its role in a French multicenter cohort of 1,356 kidney transplants.MICAmismatches w...
Antigen discovery technologies have largely focused on major histocompatibility complex (MHC) class I-restricted human T cell receptors (TCRs), leaving methods for MHC class II-restricted and mouse TCR reactivities relatively undeveloped. Here we present
To study the genetic regulation of the major histocompatibility complex (MHC) class-I, a MHC class-I promoter DNA fragment was isolated and characterized for the first time. Semi-degenerate was performed on genomic DNA and the resulting product was isolated, subcloned and sequenced. Sequence compa...
We have cloned a cDNA encoding the presumptive Fc-binding subunit, p51, and its predicted primary structure has three extracellular domains and a transmembrane region which are all homologous to the corresponding domains of class I major histocompatibility complex (MHC) antigens. This is the first ...
绵羊mhcclass 系统标签: mhc克隆基因bac区段绵羊xlolr 石河子大学 硕士学位论文 绵羊MHCclassI区段部分BAC克隆基因组成与结构分析 姓名:***申请学位级别:硕士 专业:生物化学与分子生物学 指导教师:**峰 20100511 绵羊MHCclassI区段部分BAC克隆基因组成与结构分析 I 摘要 目的:以中国美利奴羊BAC文库中含有MHC片段的3...
美利奴绵羊MHCClassI区段的基因。 结论: 1.现在生物研究很大程度上已经脱离不了生物信息学,采用生物信息学的方法,可以为 我们更好的进行研究,在遇到很复杂的实验问题,尤其在基因组序列组成与功能研究方 面,生物信息学更是占有重要地位,实验结果也显示用生物信息学的方法可以更有效的, ...
Within these clones we have demonstrated the presence of two class I genes, one of which is HLA-E , and of at least three Hpa II tiny fragment (HTF) islands, corresponding to three putative new transcribed sequences. End clones, which are of particular interest in the extension and ...
Jordanova ES, Gorter A, Ayachi O, Prins F, Durrant LG, Kenter GG, van der Burg SH, Fleuren GJ: Human leukocyte antigen class I, MHC class I chain-related molecule A, and CD8+/regulatory T-cell ratio: which variable determines survival of cervical cancer patients?. Clin Cancer Res. 200...
Previous studies have reported the effect of the human leukocyte antigen (HLA) molecules in the immune response regulation of Trypanosoma cruzi infection, and the association of HLA antigens with heart damage. We studied the major histocompatibility complex (MHC) class I (HLA-A and HLA-B), and...