Most of us know that feeling of trying to retrieve a memory that does not come right away. You might be watching a romantic comedy featuring that famous character actor who always plays the best friend and find yourself unable to recall her name (it’s Judy Greer). While memory retrieval ...
Chromatin remodeling is a complex molecular and structural process that involves the dynamic regulation of nucleosomes through different epigenetic mechanisms including histone posttranslational modifications (PTMs), DNA methylation and RNA interference [15–17]. In the rodent brain, several histone PTMs ...
Iron homeostasis disturbance has been implicated in Alzheimer’s disease (AD), and excess iron exacerbates oxidative damage and cognitive defects. Ferroptosis is a nonapoptotic form of cell death dependent upon intracellular iron. However, the involvemen
PKMz activity is not required for the processing of contextually imprecise or procedural information, indicating that PKMz may be involved in the maintenance of specific types of memories. Extinction is an active learning process that suppresses a previously conditioned response (Peters et al, 2009)....
But here's the rub: That tangy paste served up at nearly all sushi bars — even the ones in Japan — is almost certainly an impostor. Far more common than the real thing is a convincing fraud, usually made of ordinary white horseradish, dyed green. ...
He wore a tall pointed grey hat, a long grey cloak, and a silver scarf. He had a long white beard and bushy eyebrows that stuck out beyond the brim of his hat. (Tolkien, 2005, p. 25) Whenever a new character is introduced in a story, certain details about the appearance of the ...
The current study concerns a specific aspect of this retrieval process—the manner in which an initial partial retrieval of a memory might or might not lead to full retrieval. A classic example of this is the tip-of-the-tongue phenomenon (Brown & McNeill, 1966), in which an individual ...
The process of planning future saccades corresponds well with some definitions of attention3,4, but contrasts with others5,6,7. It is argued here that attention is frequently used to refer to two very different phenomena. One relates to salience, and is fundamentally a property of action ...
Moderate stress increases memory and facilitates adaptation. In contrast, intense stress can induce pathological memories as observed in post-traumatic stress disorders (PTSD). A shift in the balance between the expression of tPA and PAI-1 proteins is re
in which itwould have beenmoral. The effect occurs for immediate counterfactuals and reflective ones, but is greater when participants create an immediate counterfactual first, and diminished when they create a reflective one first. The effect also occurs for unreasonable actions. We discuss the ...